自2008年起,国际甲状腺联盟(ITF)将每年的5月25日定为世界甲状腺日(World Thyroid Day),该节日所在的一周为“国际甲状腺知识宣传周”,旨在提升公众对甲状腺健康重要性的认识,并促进全球范围内对甲状腺疾病的研究与防治。2024年的主题为“甲状腺疾病是非传染性疾病”。
甲状腺,这个位于颈部前方的微小蝴蝶状腺体,虽然体积不大,对于调节人体新陈代谢速率、影响生长发育乃至情绪平衡至关重要,其分泌的甲状腺激素(T3与T4)触及全身每个细胞,确保能量的有效利用。
甲状腺疾病是一系列影响甲状腺功能的病症,大致可分为两大类:一类是甲状腺激素产生过多或过少导致的功能性异常,另一类是甲状腺结构本身的改变,如结节或肿瘤。
探究这些疾病的根源,科学家们发现其发病机制错综复杂,涉及遗传因素、环境条件与自身免疫反应的相互作用。例如,Graves病(毒性弥漫性甲状腺肿)中,免疫系统错误攻击甲状腺,引发过度活跃;相反地,桥本甲状腺炎则是甲状腺遭受自身免疫系统破坏,导致激素生产不足。此外,碘摄入不当与特定化学物质暴露亦被视为风险因素之一。
近年来,甲状腺疾病治疗药物的研发聚焦于针对性更强、副作用更小的新型药物开发,特别是针对自身免疫性甲状腺疾病和甲状腺癌的创新疗法。比如,针对Graves病中TSH受体抗体的新型拮抗剂开发,以精准阻断过度活跃的甲状腺刺激;甲状腺眼病领域,Tepezza的成功引入为通过抑制IGF-1R缓解症状树立了新标杆,并激励了对更多创新靶点的探索。此外,研究还着重于探索甲状腺癌的靶向治疗,如针对VEGFR、BRAF突变的酪氨酸激酶抑制剂。
j9九游会登录入口首页生物长期致力于为科研工作者提供高质量的蛋白、抗体、ELISA试剂盒等工具类科研试剂产品,鉴于甲状腺疾病研究的重要性与迫切性,在此特别整理了一系列与甲状腺疾病研究相关的20余种热门靶点及相关试剂产品列举如下,供您选择:
甲状腺研究相关ELISA试剂盒:
产品名称 | 货号 | 靶点 | 检测范围 | 灵敏度 |
---|---|---|---|---|
Human Serine/threonine-protein kinase B-raf(BRAF) ELISA kit | CSB-EL002791HU | BRAF | 31.25 pg/mL-2000 pg/mL | 7.8 pg/mL |
Mouse C-Reactive Protein,CRP ELISA Kit | CSB-E07923m(1) | CRP | 5 ng/mL-4000 ng/mL | 5 ng/mL |
Rabbit C-Reactive Protein,CRP ELISA Kit | CSB-E06847Rb | CRP | 7.8 pg/mL-2000 pg/mL | 2 pg/mL |
Rat C-Reactive Protein,CRP ELISA Kit | CSB-E07922r | CRP | 31.25 ng/mL-2000 ng/mL | 7.81 ng/mL |
Mouse C-Reactive Protein,CRP ELISA Kit | CSB-E07923m | CRP | 15.6 ng/mL-1000 ng/mL | 3.9 ng/mL |
Pig C-reactive protein,CRP ELISA Kit | CSB-E08163p | CRP | 0.625 ng/mL-40 ng/mL | 0.156 ng/mL |
Bovine C-reactive protein,CRP ELISA Kit | CSB-E08577b | CRP | 1.25 ng/mL-80 ng/mL | 1.25 ng/mL |
Canine C-Reactive Protein,CRP ELISA Kit | CSB-E14262c | CRP | 0.312 μg/mL-20 μg/mL | 0.078 μg/mL |
Sheep C-reactive protein(CRP) ELISA Kit | CSB-E15081Sh | CRP | 0.625 μg/mL-40 μg/mL | 0.156 μg/mL |
Hamster C-reactive protein(CRP) ELISA Kit | CSB-EL005991HA | CRP | 12.5 ng/mL-800 ng/mL | 3.12 ng/mL |
Human Catenin beta-1 (CTNNB1/CTNNB/OK/SW-cl.35/PRO2286) ELISA kit | CSB-E08963h | CTNNB1 | 15.6 pg/mL-1000 pg/mL | 3.9 pg/mL |
Mouse β-catenin,β-cat ELISA Kit | CSB-E11307m | CTNNB1 | 0.156 ng/mL-10 ng/mL | 0.039 ng/mL |
Human epidermal growth factor receptor,EGFR ELISA Kit | CSB-E12124h | EGFR | 0.312 ng/mL-20 ng/mL | 0.019 ng/mL |
Mouse Insulin-like growth factor 1,IGF-1 ELISA Kit | CSB-E04581m | IGF1 | 0.156 ng/mL-10 ng/mL | 0.151 ng/mL |
Rat Insulin-like growth factor 1,IGF-1 ELISA Kit | CSB-E04582r | IGF1 | 0.156 ng/mL-10 ng/mL | 0.151 ng/mL |
Pig insulin-like growth factors-1,IGF-1 ELISA Kit | CSB-E06829p | IGF1 | 6.25 ng/mL-400 ng/mL | 1.56 ng/mL |
Rabbit Insulin-like growth factor 1,IGF-1 ELISA Kit | CSB-E06994Rb | IGF1 | 0.156 ng/mL-10 ng/mL | 0.039 ng/mL |
Bovine Insulin-like growth factor 1,IGF-1 ELISA Kit | CSB-E08893b | IGF1 | 0.75 ng/mL-60 ng/mL | 0.94 ng/mL |
Chicken Insulin-like growth factors 1,IGF-1 ELISA Kit | CSB-E09867Ch | IGF1 | 125 pg/mL-2000 pg/mL | 125 pg/mL |
Sheep insulin-like growth factor 1,IGF-1 ELISA Kit | CSB-E13753Sh | IGF1 | 15.6 ng/mL-1000 ng/mL | 3.9 ng/mL |
甲状腺研究相关重组蛋白:
产品名称 | 货号 | 靶点 | 来源 | 蛋白标签 |
---|---|---|---|---|
Recombinant Mouse Thyrotropin receptor (Tshr), partial | CSB-BP025131MO | Tshr | Baculovirus | N-terminal 6xHis-tagged |
Recombinant Marmota monax Tumor necrosis factor (TNF), partial | CSB-BP523593MQG | TNF | Baculovirus | N-terminal 10xHis-tagged |
Recombinant Human Catenin beta-1 (CTNNB1) | CSB-EP006169HU | CTNNB1 | E.coli | N-terminal GST-tagged |
Recombinant Human Epidermal growth factor receptor (EGFR), partial | CSB-EP007479HU3 | EGFR | E.coli | N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged |
Recombinant Human Interleukin-6 (IL6) | CSB-EP011664HU | IL6 | E.coli | N-terminal 6xHis-tagged |
Recombinant Sheep Interleukin-6 (IL6) | CSB-EP011664SH | IL6 | E.coli | N-terminal GST-tagged |
Recombinant Human GTPase KRas (KRAS), partial | CSB-EP012493HU1 | KRAS | E.coli | N-terminal 6xHis-tagged |
Recombinant Human Homeobox protein Nkx-2.1 (NKX2-1) | CSB-EP015841HU | NKX2-1 | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
Recombinant Human Paired box protein Pax-8 (PAX8) | CSB-EP017494HU | PAX8 | E.coli | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
Recombinant Human Telomerase reverse transcriptase (TERT), partial | CSB-EP023391HU | TERT | E.coli | N-terminal 6xHis-tagged |
Recombinant Mouse Telomerase reverse transcriptase (Tert), partial | CSB-EP023391MO | Tert | E.coli | N-terminal 6xHis-SUMO-tagged |
Recombinant Rat Thyroglobulin (Tg), partial | CSB-EP023442RA | Tg | E.coli | N-terminal 6xHis-SUMO-tagged |
Recombinant Bovie Tumor necrosis factor (TNF), partial | CSB-EP023955BO | TNF | E.coli | N-terminal 6xHis-tagged |
Recombinant Bovie Tumor necrosis factor (TNF), partial | CSB-EP023955BOe0 | TNF | E.coli | N-terminal GST-tagged |
Recombinant Human Tumor necrosis factor (TNF), partial | CSB-EP023955HU | TNF | E.coli | N-terminal 6xHis-tagged |
Recombinant Mouse Tumor necrosis factor (Tnf), partial | CSB-EP023955MO1 | Tnf | E.coli | N-terminal 6xHis-SUMO-tagged |
Recombinant Sheep Tumor necrosis factor (TNF), partial | CSB-EP023955SH | TNF | E.coli | N-terminal GST-tagged |
Recombinant Human Cellular tumor antigen p53 (TP53) | CSB-EP024077HU | TP53 | E.coli | N-terminal 6xHis-SUMO-tagged |
Recombinant Mouse Cellular tumor antigen p53 (Tp53) | CSB-EP024077MO | Tp53 | E.coli | N-terminal 6xHis-SUMO-tagged |
Recombinant Pig Vascular endothelial growth factor A (VEGFA) | CSB-EP025833PI | VEGFA | E.coli | N-terminal 6xHis-tagged |
甲状腺研究相关抗体:
● 重组抗体:
产品名称 | 货号 | 靶点 | 反应种属 | 应用范围 |
---|---|---|---|---|
Phospho-BRAF (T401) Recombinant Monoclonal Antibody | CSB-RA002791A401phHU | BRAF | Human | ELISA, WB, IF |
BRAF Recombinant Monoclonal Antibody | CSB-RA171021A0HU | BRAF | Human | ELISA, IHC |
CRP Recombinant Monoclonal Antibody | CSB-RA988767A0HU | CRP | Human | ELISA, IHC |
Phospho-CTNNB1 (S33/S37) Recombinant Monoclonal Antibody | CSB-RA006169A33phHU | CTNNB1 | Human | ELISA, IF |
CTNNB1 Recombinant Monoclonal Antibody | CSB-RA155605A0HU | CTNNB1 | Human | ELISA, IHC |
CTNNB1 Recombinant Monoclonal Antibody | CSB-RA006169MA1HU | CTNNB1 | Human | ELISA, IHC, IF, FC |
Phospho-EGFR (Y1092) Recombinant Monoclonal Antibody | CSB-RA007479A1092phHU | EGFR | Human | ELISA, WB |
Phospho-EGFR (Y1068) Recombinant Monoclonal Antibody | CSB-RA007479A1068phHU | EGFR | Human | ELISA, WB |
EGFR Recombinant Monoclonal Antibody | CSB-RA159341A0HU | EGFR | Human | ELISA, WB, IHC, IF, FC |
EGFR Recombinant Monoclonal Antibody | CSB-RA794061A0HU | EGFR | Human | ELISA, WB, IHC |
EGFR Recombinant Monoclonal Antibody | CSB-RA159341MA1HU | EGFR | Human | ELISA, IHC, FC |
IL6 Recombinant Monoclonal Antibody | CSB-RA011664MA1HU | IL6 | Human | ELISA |
INS Recombinant Monoclonal Antibody | CSB-RA584163A0HU | INS | Human | ELISA, IHC |
Phospho-MTOR (S2481) Recombinant Monoclonal Antibody | CSB-RA008968A2481phHU | MTOR | Human | ELISA, WB, IF |
Phospho-MTOR (S2448) Recombinant Monoclonal Antibody | CSB-RA008968A2448phHU | MTOR | Human | ELISA, WB, IHC, IF |
NKX2-1 Recombinant Monoclonal Antibody | CSB-RA181189A0HU | NKX2-1 | Human | ELISA, WB, IHC, FC |
PAX8 Recombinant Monoclonal Antibody | CSB-RA248028A0HU | PAX8 | Human | ELISA, IHC |
Phospho-PTEN (S380) Recombinant Monoclonal Antibody | CSB-RA018964A380phHU | PTEN | Human | ELISA, WB |
RET Recombinant Monoclonal Antibody | CSB-RA288083A0HU | RET | Human | ELISA, FC |
TERT Recombinant Monoclonal Antibody | CSB-RA798840A0HU | TERT | Human | ELISA, IHC |
● 单克隆抗体:
产品名称 | 货号 | 靶点 | 反应种属 | 应用范围 |
---|---|---|---|---|
CRP Monoclonal Antibody | CSB-MA027411E0m | CRP | Human | ELISA, IHC |
CTNNB1 Monoclonal Antibody | CSB-MA000223 | CTNNB1 | Human,Mouse,Rat | ELISA, WB, IHC |
CTNNB1 Monoclonal Antibody | CSB-MA080197 | CTNNB1 | Human,Mouse,Rat | ELISA, WB, IHC |
CTNNB1 Monoclonal Antibody | CSB-MA922448 | CTNNB1 | Human,Mouse,Rat | ELISA, WB, IHC |
CTNNB1 Monoclonal Antibody | CSB-MA907551 | CTNNB1 | Human | ELISA, IHC |
EGFR Monoclonal Antibody | CSB-MA000199 | EGFR | Human | ELISA, WB, IHC, IF |
EGFR Monoclonal Antibody | CSB-MA000293 | EGFR | Human | ELISA, WB |
IL6 Monoclonal Antibody | CSB-MA067571A0m | IL6 | Human | ELISA, WB, IHC |
PTH Monoclonal Antibody | CSB-MA0189871A0m | PTH | Human | ELISA |
TNF Monoclonal Antibody | CSB-MA084771A0m | TNF | Bovine | ELISA |
TNF Monoclonal Antibody | CSB-MA080271 | TNF | Human,Mouse,Rat | ELISA, WB, IHC |
TNF Monoclonal Antibody | CSB-MA080272 | TNF | Human,Mouse,Rat | ELISA, WB, IHC |
TP53 Monoclonal Antibody | CSB-MA0240771A0m | TP53 | Human | ELISA, WB, IHC |
TP53 Monoclonal Antibody | CSB-MA000208 | TP53 | Human | ELISA, WB, IHC, IF |
TP53 Monoclonal Antibody | CSB-MA989534 | TP53 | Human | ELISA, WB |
TP53 Monoclonal Antibody | CSB-MA189580 | TP53 | Human,Dog,Mouse,Rat | ELISA, WB |
● 多克隆抗体:
产品名称 | 货号 | 靶点 | 反应种属 | 应用范围 |
---|---|---|---|---|
BRAF Antibody | CSB-PA002791LA01HU | BRAF | Human | ELISA, IHC, IF |
BRAF Antibody | CSB-PA003928 | BRAF | Human, Mouse, Rat | ELISA, WB, IHC |
BRAF Antibody | CSB-PA003929 | BRAF | Human, Mouse | ELISA, WB, IHC, IF |
Phospho-BRAF (S602) Antibody | CSB-PA050147 | BRAF | Human, Mouse, Rat | ELISA, WB, IHC |
Phospho-BRAF (T753) Antibody | CSB-PA050146 | BRAF | Human, Mouse, Rat | ELISA, WB |
Phospho-BRAF (T599) Antibody | CSB-PA050149 | BRAF | Human, Mouse, Rat | ELISA, IHC |
BRAF Antibody | CSB-PA050150 | BRAF | Human, Mouse, Rat | ELISA, WB |
BRAF Antibody | CSB-PA050151 | BRAF | Human, Mouse, Rat | ELISA, IHC |
Phospho-BRAF (S446) Antibody | CSB-PA050148 | BRAF | Human, Mouse | ELISA, WB, IHC |
BRAF Antibody | CSB-PA050152 | BRAF | Human, Mouse | ELISA, WB, IHC |
BRAF Antibody | CSB-PA587286 | BRAF | Human, Mouse | ELISA, WB, IHC |
BRAF Antibody | CSB-PA163656 | BRAF | Human, Mouse | ELISA, WB, IHC |
BRAF Antibody | CSB-PA179620 | BRAF | Human, Mouse | ELISA, WB, IHC |
BRAF (Ab-753) Antibody | CSB-PA921529 | BRAF | Human, Mouse | ELISA, WB |
BRAF (Ab-446) Antibody | CSB-PA134950 | BRAF | Human, Mouse | ELISA, WB, IHC |
Phospho-BRAF (Ser446) Antibody | CSB-PA575128 | BRAF | Human, Mouse | ELISA, WB |
Phospho-BRAF (Thr753) Antibody | CSB-PA985068 | BRAF | Human, Mouse, Rat | ELISA, WB |
Phospho-BRAF (Thr599) Antibody | CSB-PA243682 | BRAF | Human, Mouse, Rat | ELISA, IHC |
CCDC6 Antibody | CSB-PA623068LA01HU | CCDC6 | Human | ELISA, WB, IHC, IF |
CRP Antibody | CSB-PA06079A0Rb | CRP | Human | ELISA, WB, IHC |