BRAF
BRAF，即B型快速反应蛋白激酶，它是一种丝氨酸/苏氨酸激酶，属于RAF家族成员。BRAF由BRAF基因编码，广泛存在于多种组织中，尤其是在神经细胞和皮肤细胞中。其作用机制涉及与RAS蛋白的激活形式结合后，发生磷酸化和二聚化，进而激活下游的MEK/ERK信号通路，该通路在细胞增殖、分化、迁移和凋亡等过程中发挥关键作用。BRAF的生物学意义在于其在调控细胞周期、细胞应激反应以及细胞内信号传递中的核心作用。BRAF基因的突变，特别是在其激酶结构域中，与多种癌症的发生发展有关，如黑色素瘤、结直肠癌等，因此BRAF也是癌症治疗中的一个重要靶点。
BRAF Antibodies
BRAF for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA575128 | Phospho-BRAF (Ser446) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA985068 | Phospho-BRAF (Thr753) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA134950 | BRAF (Ab-446) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA921529 | BRAF (Ab-753) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA243682 | Phospho-BRAF (Thr599) Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA003928 | BRAF Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA003929 | BRAF Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA050146 | Phospho-BRAF (T753) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA050147 | Phospho-BRAF (S602) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA050148 | Phospho-BRAF (S446) Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA050149 | Phospho-BRAF (T599) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA050150 | BRAF Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA050151 | BRAF Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA050152 | BRAF Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA587286 | BRAF Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA163656 | BRAF Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA179620 | BRAF Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA002791LA01HU | BRAF Antibody | Human | ELISA, IHC, IF |
| CSB-PA002791LB01HU | BRAF Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002791LC01HU | BRAF Antibody, FITC conjugated | Human | |
| CSB-PA002791LD01HU | BRAF Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA002791A401phHU | Phospho-BRAF (T401) Recombinant Monoclonal Antibody | Human | ELISA, WB, IF |
| CSB-RA171021A0HU | BRAF Recombinant Monoclonal Antibody | Human | ELISA, IHC |
BRAF Proteins
BRAF Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002791CH CSB-EP002791CH CSB-BP002791CH CSB-MP002791CH CSB-EP002791CH-B |
Recombinant Chicken Serine/threonine-protein kinase B-raf (BRAF), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAF Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002791HU CSB-EP002791HU CSB-BP002791HU CSB-MP002791HU CSB-EP002791HU-B |
Recombinant Human Serine/threonine-protein kinase B-raf (BRAF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAF Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002791MO CSB-EP002791MO CSB-BP002791MO CSB-MP002791MO CSB-EP002791MO-B |
Recombinant Mouse Serine/threonine-protein kinase B-raf (Braf), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAF Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002791DXJ CSB-EP002791DXJ CSB-BP002791DXJ CSB-MP002791DXJ CSB-EP002791DXJ-B |
Recombinant Coturnix coturnix japonica Serine/threonine-protein kinase B-raf (BRAF), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAF Proteins for Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP325121EZX CSB-EP325121EZX CSB-BP325121EZX CSB-MP325121EZX CSB-EP325121EZX-B |
Recombinant Pseudomonas aeruginosa High-affinity branched-chain amino acid transport ATP-binding protein BraF (braF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAF ELISA Kit
BRAF ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL002791HU | Human Serine/threonine-protein kinase B-raf(BRAF) ELISA kit | serum, plasma, cell lysates | 7.8 pg/mL |
