GPRC5D
GPRC5D（G Protein-Coupled Receptor Class C Group 5 Member D）是一种跨膜蛋白受体，包括一个胞外区域、一个跨膜区域和一个胞浆区域。它位于细胞膜上，可以与特定的信号分子结合，从而触发细胞内信号传导。GPRC5D被发现在B细胞中高度表达，尤其是在多发性骨髓瘤（MM）细胞中。研究表明，GPRC5D在免疫细胞的活化和增殖中可能起到重要作用，尤其是在多发性骨髓瘤中，它被认为是一种潜在的治疗靶点。
更多相关阅读：孤儿受体GPRC5D：多发性骨髓瘤MM全新潜力靶点，加码GPCR药物治疗！
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验证数据
CSB-MP882153HU is detected by Mouse anti-6*His monoclonal antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D at 5 μg/mL can bind Anti-GPRC5D recombinant antibody (CSB-RA882153MA01HU), the EC50 is 8.847-10.38 ng/mL.
● GPRC5D Recombinant Monoclonal Antibody CSB-RA882153MA01HU
验证数据
The Binding Activity of Huamn GPRC5D with Anti-GPRC5D recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D(CSB-MP882153HU) at 5 μg/mL can bind Anti-GPRC5D recombinant antibody, the EC50 is 8.847-10.38 ng/mL.
GPRC5D Antibodies
GPRC5D for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA030200 | GPRC5D Antibody | Human,Mouse | WB, IF, ELISA |
| CSB-RA882153MA01HU | GPRC5D Recombinant Monoclonal Antibody | Human | ELISA |
GPRC5D Proteins
GPRC5D Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP878065MO1 CSB-EP878065MO1 CSB-BP878065MO1 CSB-MP878065MO1 CSB-EP878065MO1-B |
Recombinant Mouse G-protein coupled receptor family C group 5 member D (Gprc5d), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF878065MO | Recombinant Mouse G-protein coupled receptor family C group 5 member D (Gprc5d) | in vitro E.coli expression system |
GPRC5D Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP882153HU1 CSB-BP882153HU1 CSB-MP882153HU1 CSB-EP882153HU1-B |
Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF882153HU | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D) | in vitro E.coli expression system |
| CSB-MP882153HU | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D)-VLPs (Active) | Mammalian cell |
| CSB-EP882153HU1 | Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D), partial | E.coli |
