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GH1

生长激素-不仅仅促进长高

生长激素1(growth hormone 1,GH1)也被称为垂体生长激素,或简单地称为生长激素(GH),是生长激素/催乳激素家族中的一员。人类基因组包含5个GH相关基因:人生长激素(hGH)、人类绒毛膜生长催乳素-A(hCS-A)、人类绒毛膜生长催乳素-B(hCS-B)、人类绒毛膜生长催乳激素类似物(hCS-L)、人类生长素变异体(hGH-V)。它们是一类由脑垂体前叶嗜酸性颗粒的生长激素分泌细胞分泌的一种单一肽链的蛋白质激素,其主要作用是促进生长发育和影响代谢。此外,研究表明生长激素对神经系统疾病也具有较广泛的生理作用,特别是在神经修复和神经保护方面有比较大的作用。GH1基因的突变或缺失会导致生长激素缺乏和身材矮小。另有报道指出GH1/IGF-1途径在癌症的发生和发展过程中起到了重要的作用,GH1/IGF-1水平升高与食管癌以及大肠癌的发病风险显著关联。

Recombinant Human GH1 活性蛋白实验验证数据

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized human GH1 at 2 μg/ml can bind Biotinylated human GHR (CSB-MP009411HUj1-B), the EC50 is 2.067-3.208 ng/ml.

Excellent Bioactivity Validated by LSPR Assay

Human GH1 protein his/myc tag (CSB-MP009407HU) captured on COOH chip can bind Human GHR protein Fc tag (CSB-MP009411HU) with an affinity constant of 6.1 nM as detected by LSPR Assay.


GH1 Antibodies

GH1 for Homo sapiens (Human)

GH1 Proteins

GH1 Proteins for Capra hircus (Goat)

GH1 Proteins for Ovis aries (Sheep)

GH1 Proteins for Macaca mulatta (Rhesus macaque)

GH1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

GH1 Proteins for Felis catus (Cat) (Felis silvestris catus)

GH1 Proteins for Oryctolagus cuniculus (Rabbit)

GH1 Proteins for Bos taurus (Bovine)

GH1 Proteins for Mus musculus (Mouse)

GH1 Proteins for Sus scrofa (Pig)

GH1 Proteins for Equus caballus (Horse)

GH1 Proteins for Vulpes vulpes (Red fox)

GH1 Proteins for Mustela vison (American mink) (Neovison vison)

GH1 Proteins for Loxodonta africana (African elephant)

GH1 Proteins for Mesocricetus auratus (Golden hamster)

GH1 Proteins for Lama guanicoe pacos (Alpaca) (Lama pacos)

GH1 Proteins for Balaenoptera borealis (Sei whale) (Pollack whale)

GH1 Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

GH1 Proteins for Cervus elaphus (Red deer)

GH1 Proteins for Pan troglodytes (Chimpanzee)

GH1 Proteins for Rattus norvegicus (Rat)

GH1 Proteins for Bubalus bubalis (Domestic water buffalo)

GH1 Proteins for Trichosurus vulpecula (Brush-tailed possum)

GH1 Proteins for Spalax ehrenbergi (Middle East blind mole rat) (Nannospalax ehrenbergi)

GH1 Proteins for Acipenser guldenstadti (Caspian sturgeon) (Russian sturgeon)

GH1 Proteins for Anguilla japonica (Japanese eel)

GH1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

GH1 Proteins for Carassius auratus (Goldfish)

GH1 Proteins for Bos gaurus frontalis (Domestic gayal) (Bos frontalis)

GH1 Proteins for Balaenoptera physalus (Finback whale) (Common rorqual)

GH1 Proteins for Bos mutus grunniens (Wild yak) (Bos grunniens)

GH1 Proteins for Camelus dromedarius (Dromedary) (Arabian camel)

GH1 Proteins for Ailuropoda melanoleuca (Giant panda)

GH1 Proteins for Delphinus delphis (Saddleback dolphin) (Black sea dolphin)

GH1 Proteins for Oncorhynchus nerka (Sockeye salmon) (Salmo nerka)

GH1 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

GH1 Proteins for Monodelphis domestica (Gray short-tailed opossum)

GH1 Proteins for Cavia porcellus (Guinea pig)

GH1 Proteins for Galago senegalensis (Northern lesser bushbaby) (Senegal bushbaby)

GH1 Proteins for Nycticebus pygmaeus (Pygmy slow loris)

GH1 Proteins for Homo sapiens (Human)

GH1 ELISA Kit

GH1 ELISA Kit for Fish

GH1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

GH1 ELISA Kit for Capra hircus (Goat)

GH1 ELISA Kit for Equus caballus (Horse)

GH1 ELISA Kit for Monkey

GH1 ELISA Kit for Mus musculus (Mouse)

GH1 ELISA Kit for Ovis aries (Sheep)

GH1 ELISA Kit for Bos taurus (Bovine)

GH1 ELISA Kit for Oryctolagus cuniculus (Rabbit)

GH1 ELISA Kit for Sus scrofa (Pig)