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BTLA

BTLA(B and T Lymphocyte Attenuator)是一种细胞表面受体蛋白,对调控免疫系统起着重要作用。BTLA属于CD28免疫球蛋白超家族,包括一个细胞外免疫球蛋白样结构域、一个跨膜区域和一个细胞内信号传导结构域。BTLA是一种免疫检查点分子,用于调节免疫反应。当BTLA与其配体HVEM(Herpes病毒感染相关免疫球蛋白-样受体)相互作用时,它能够抑制T细胞的激活,减弱免疫应答,从而有助于维持免疫平衡。在癌症治疗中,研究人员研究如何通过干预BTLA和HVEM的相互作用来增强T细胞的免疫反应,以对抗肿瘤细胞。此外,了解BTLA的调节作用有助于我们更好地理解自身免疫疾病的发病机制,并可能为开发治疗方法提供新的思路。

热销产品

Recombinant Human B- and T-lymphocyte attenuator(BTLA),partial (Active) CSB-MP773799HU

验证数据

SDS
CSB-MP773799HU-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP773799HU

Activity: Measured by its binding ability in a functional ELISA. Immobilized BTLA at 5 μg/ml can bind biotinylated human TNFRSF14 (CSB-MP842173HU-A), the EC50 is 137.8-233.4 ng/ml.

BTLA Antibodies

BTLA for Homo sapiens (Human)

BTLA Proteins

BTLA Proteins for Mus musculus (Mouse)

BTLA Proteins for Rattus norvegicus (Rat)

BTLA Proteins for Homo sapiens (Human)

BTLA ELISA Kit

BTLA ELISA Kit for Homo sapiens (Human)

BTLA ELISA Kit for Mus musculus (Mouse)