BTLA
BTLA(B and T Lymphocyte Attenuator)是一种细胞表面受体蛋白,对调控免疫系统起着重要作用。BTLA属于CD28免疫球蛋白超家族,包括一个细胞外免疫球蛋白样结构域、一个跨膜区域和一个细胞内信号传导结构域。BTLA是一种免疫检查点分子,用于调节免疫反应。当BTLA与其配体HVEM(Herpes病毒感染相关免疫球蛋白-样受体)相互作用时,它能够抑制T细胞的激活,减弱免疫应答,从而有助于维持免疫平衡。在癌症治疗中,研究人员研究如何通过干预BTLA和HVEM的相互作用来增强T细胞的免疫反应,以对抗肿瘤细胞。此外,了解BTLA的调节作用有助于我们更好地理解自身免疫疾病的发病机制,并可能为开发治疗方法提供新的思路。
热销产品
Recombinant Human B- and T-lymphocyte attenuator(BTLA),partial (Active) CSB-MP773799HU
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized BTLA at 5 μg/ml can bind biotinylated human TNFRSF14 (CSB-MP842173HU-A), the EC50 is 137.8-233.4 ng/ml.
BTLA Antibodies
BTLA for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA921165 | BTLA Antibody | Human | ELISA,WB |
CSB-PA007471 | BTLA Antibody | Human | WB, ELISA |
CSB-PA100659 | BTLA Antibody | Human | ELISA,IHC |
CSB-PA921825 | BTLA Antibody | Human | ELISA,IHC |
CSB-PA446647 | BTLA Antibody | Human | IHC,ELISA |
BTLA Proteins
BTLA Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP742519MO CSB-EP742519MO CSB-BP742519MO CSB-MP742519MO CSB-EP742519MO-B |
Recombinant Mouse B- and T-lymphocyte attenuator (Btla), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BTLA Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP744141RA CSB-EP744141RA CSB-BP744141RA CSB-MP744141RA CSB-EP744141RA-B |
Recombinant Rat B- and T-lymphocyte attenuator (Btla), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BTLA Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP773799HU CSB-EP773799HU CSB-BP773799HU CSB-EP773799HU-B |
Recombinant Human B- and T-lymphocyte attenuator (BTLA), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP773799HU | Recombinant Human B- and T-lymphocyte attenuator (BTLA), partial (Active) | Mammalian cell |
CSB-MP773799HU-B | Recombinant Human B- and T-lymphocyte attenuator (BTLA), partial,Biotinylated | Mammalian cell |
BTLA ELISA Kit
BTLA ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL002868HU | Human B- and T-lymphocyte attenuator(BTLA) ELISA kit | serum, plasma, tissue homogenates | 0.11 ng/mL |
BTLA ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL002868MO | Mouse B- and T-lymphocyte attenuator(BTLA) ELISA kit | serum, plasma, tissue homogenates | 0.156 ng/mL |