Il6
IL-6（白细胞介素-6）是一种糖蛋白，由184个氨基酸残基组成，分子量约为21~26 kDa。它包含四个半胱氨酸残基，形成两个分子内二硫键，这使得IL-6的结构稳定。IL-6的分泌形式可以是游离的，也可以与可溶性IL-6受体（sIL-6R）结合形成复合物。IL-6具有多种生物学功能，包括但不限于：免疫调节、炎症反应、造血作用：IL-6可以促进骨髓造血干细胞的增殖和分化，参与红细胞、血小板等血液成分的生成。IL-6与多种疾病的发生和发展密切相关，如风湿性关节炎、多发性硬化症、糖尿病、心血管疾病以及某些类型的肿瘤等。 IL-6的信号传导主要通过以下两种途径实现：经典信号通路：IL-6首先与膜结合的IL-6受体（mIL-6R）结合，然后招募并激活gp130分子（一个信号转导蛋白）。激活的gp130触发JAK（Janus激酶）的磷酸化，进而激活STAT3（信号转导和转录激活因子3）。活化的STAT3进入细胞核，调控基因表达。反式信号通路：在缺乏mIL-6R的细胞上，IL-6可以与sIL-6R结合，形成IL-6/sIL-6R复合物。这个复合物随后与细胞表面的gp130结合并激活信号通路。这种反式信号通路使得IL-6能够在更广泛的细胞类型中发挥作用。异常的IL-6表达和信号传导可能导致疾病的发生和发展。因此，对IL-6的深入研究有助于我们更好地理解其在疾病中的作用，并为疾病的治疗提供新的思路和方法。
热销产品
IL6 Recombinant Monoclonal Antibody
验证数据
The Binding Activity of Human IL6 with Anti-IL6 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL6 (CSB-YP011664HU) at 2 μg/mL can bind Anti-IL6 recombinant antibody. The EC50 is 35.80-41.82 ng/mL.
Il6 Antibodies
Il6 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA06757B0Rb | IL6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06757C0Rb | IL6 Antibody, FITC conjugated | Human | |
| CSB-PA06757A0Rb | IL6 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA06757D0Rb | IL6 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA005546 | IL6 Antibody | Human | WB, ELISA |
| CSB-RA011664MA1HU | IL6 Recombinant Monoclonal Antibody | Human | ELISA |
Il6 Proteins
Il6 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664BO CSB-BP011664BO CSB-MP011664BO CSB-EP011664BO-B |
Recombinant Bovine Interleukin-6 (IL6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664DO CSB-EP011664DO CSB-BP011664DO CSB-MP011664DO CSB-EP011664DO-B |
Recombinant Dog Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664PI CSB-EP011664PI CSB-BP011664PI CSB-MP011664PI CSB-EP011664PI-B |
Recombinant Pig Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664SH | Recombinant Sheep Interleukin-6 (IL6) | Yeast |
| CSB-EP011664SH | Recombinant Sheep Interleukin-6 (IL6) | E.coli |
| CSB-BP011664SH CSB-MP011664SH CSB-EP011664SH-B |
Recombinant Sheep Interleukin-6 (IL6) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664CA CSB-EP011664CA CSB-BP011664CA CSB-MP011664CA CSB-EP011664CA-B |
Recombinant Cat Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664MOW CSB-EP011664MOW CSB-BP011664MOW CSB-MP011664MOW CSB-EP011664MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003101MOW | Recombinant Macaca mulatta Interleukin-6 protein (IL6) | E.Coli |
Il6 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-BP011664HU CSB-MP011664HU CSB-EP011664HU-B |
Recombinant Human Interleukin-6 (IL6) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001741HU | Recombinant Human Interleukin-6 protein (IL6) | E.Coli |
| CSB-EP011664HU | Recombinant Human Interleukin-6 (IL6),Escherichia Coli | E.coli |
| CSB-AP004301HU | Recombinant Human Interleukin-6 (IL6) (Active) | E.coli |
| CSB-AP005841HU | Recombinant Human Interleukin-6 (IL6) (Active) (GMP) | E.Coli |
| CSB-YP011664HU | Recombinant Human Interleukin-6(IL6) (Active) | yeast |
| CSB-MP011664HU-B | Recombinant Human Interleukin-6 (IL6), Biotinylated | Mammalian cell |
Il6 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011664MO CSB-EP011664MO CSB-BP011664MO CSB-MP011664MO CSB-EP011664MO-B |
Recombinant Mouse Interleukin-6 (Il6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003321MO | Recombinant Mouse Interleukin-6 protein (Il6) (Active) | E.Coli |
Il6 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP305249MOV CSB-EP305249MOV CSB-BP305249MOV CSB-MP305249MOV CSB-EP305249MOV-B |
Recombinant Macaca fascicularis Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP322670RA CSB-EP322670RA CSB-BP322670RA CSB-MP322670RA CSB-EP322670RA-B |
Recombinant Rat Interleukin-6 (Il6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Mustela vison (American mink) (Neovison vison)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP336891MVE CSB-EP336891MVE CSB-BP336891MVE CSB-MP336891MVE CSB-EP336891MVE-B |
Recombinant Mustela vison Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP342020DRI CSB-EP342020DRI CSB-BP342020DRI CSB-MP342020DRI CSB-EP342020DRI-B |
Recombinant Cercocebus atys Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP385261MOH CSB-EP385261MOH CSB-BP385261MOH CSB-MP385261MOH CSB-EP385261MOH-B |
Recombinant Mustela putorius furo Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Sparus aurata (Gilthead sea bream)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP466936FJX CSB-EP466936FJX CSB-BP466936FJX CSB-MP466936FJX CSB-EP466936FJX-B |
Recombinant Sparus aurata Interleukin-6 (il6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Marmota monax (Woodchuck)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP518577MQG CSB-EP518577MQG CSB-BP518577MQG CSB-MP518577MQG CSB-EP518577MQG-B |
Recombinant Marmota monax Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP610956OEI CSB-EP610956OEI CSB-BP610956OEI CSB-MP610956OEI CSB-EP610956OEI-B |
Recombinant Oncorhynchus mykiss Interleukin-6 (il6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Orcinus orca (Killer whale)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP630696OEP CSB-EP630696OEP CSB-BP630696OEP CSB-MP630696OEP CSB-EP630696OEP-B |
Recombinant Orcinus orca Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Capra hircus (Goat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP631708GO CSB-EP631708GO CSB-BP631708GO CSB-MP631708GO CSB-EP631708GO-B |
Recombinant Goat Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Phoca vitulina (Harbor seal)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP631730EUR CSB-EP631730EUR CSB-BP631730EUR CSB-MP631730EUR CSB-EP631730EUR-B |
Recombinant Phoca vitulina Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Vulpes vulpes (Red fox)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP635622VFW CSB-EP635622VFW CSB-BP635622VFW CSB-MP635622VFW CSB-EP635622VFW-B |
Recombinant Vulpes vulpes Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP640800BAAW CSB-EP640800BAAW CSB-BP640800BAAW CSB-MP640800BAAW CSB-EP640800BAAW-B |
Recombinant Bubalus carabanensis Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Macaca thibetana (Pere David's macaque) (Tibetan macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP686313MDAO CSB-EP686313MDAO CSB-BP686313MDAO CSB-MP686313MDAO CSB-EP686313MDAO-B |
Recombinant Macaca thibetana Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Bubalus bubalis (Domestic water buffalo)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP740930BWX CSB-EP740930BWX CSB-BP740930BWX CSB-MP740930BWX CSB-EP740930BWX-B |
Recombinant Bubalus bubalis Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP760907TKY CSB-EP760907TKY CSB-BP760907TKY CSB-MP760907TKY CSB-EP760907TKY-B |
Recombinant Takifugu rubripes Interleukin-6 (il6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Camelus bactrianus (Bactrian camel)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP772948CVZ CSB-EP772948CVZ CSB-BP772948CVZ CSB-MP772948CVZ CSB-EP772948CVZ-B |
Recombinant Camelus bactrianus Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Lama glama (Llama)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP803040LBS CSB-BP803040LBS CSB-EP803040LBS-B |
Recombinant Lama glama Interleukin-6 (IL6) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
Il6 Proteins for Saimiri sciureus (Common squirrel monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP847583SWD CSB-EP847583SWD CSB-BP847583SWD CSB-MP847583SWD CSB-EP847583SWD-B |
Recombinant Saimiri sciureus Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP856206CH CSB-EP856206CH CSB-BP856206CH CSB-MP856206CH CSB-EP856206CH-B |
Recombinant Chicken Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP856767HO CSB-EP856767HO CSB-BP856767HO CSB-MP856767HO CSB-EP856767HO-B |
Recombinant Horse Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP863071RB | Recombinant Rabbit Interleukin-6 (IL6) | Yeast |
| CSB-EP863071RB CSB-BP863071RB CSB-MP863071RB CSB-EP863071RB-B |
Recombinant Rabbit Interleukin-6 (IL6) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 Proteins for Delphinapterus leucas (Beluga whale)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP893174DJB CSB-EP893174DJB CSB-BP893174DJB CSB-MP893174DJB CSB-EP893174DJB-B |
Recombinant Delphinapterus leucas Interleukin-6 (IL6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il6 ELISA Kit
Il6 ELISA Kit for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12899B | Bovine Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 2.5 pg/mL |
Il6 ELISA Kit for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08549Ch | Chicken Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
Il6 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E11260c | Dog Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 0.39 pg/mL |
Il6 ELISA Kit for Capra hircus (Goat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E14360G | Goat Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 0.39 pg/mL |
Il6 ELISA Kit for Monkey
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E10050Mo | Monkey Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
Il6 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04639m | Mouse Interleukin 6,IL-6 ELISA KIT |
Il6 ELISA Kit for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E06786p | Pig Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 0.31 pg/mL |
Il6 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E06903Rb | Rabbit Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
Il6 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04640r | Rat Interleukin 6,IL-6 ELISA KIT | serum, plasma, tissue homogenates | 0.078 pg/ml |
Il6 ELISA Kit for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E10116Sh | Sheep Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 2 pg/mL |
Il6 ELISA Kit for Fish
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E13258Fh | Fish Interleukin 6,IL-6 ELISA Kit | serum, plasma, tissue homogenates | 12.5 pg/mL |
Il6 ELISA Kit for Equus caballus (Horse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E16634Hs | Horse Interleukin 6(IL-6)ELISA Kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
Il6 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04638h | Human Interleukin 6,IL-6 ELISA KIT | serum, plasma, cell culture supernates, tissue homogenates, urine | 2.453 pg/mL |
