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TNFSF12 Antibody

  • 货号:
    CSB-PA152148
  • 规格:
    ¥2024
  • 图片:
    • Western blot analysis of extracts from COLO cells, HUVEC cells and 293 cells, using TNF12 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.
    • Immunofluorescence analysis of HeLa cells, using TNF12 antibody.
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) TNFSF12 Polyclonal antibody
  • Uniprot No.:
    O43508
  • 基因名:
    TNFSF12
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from internal of Human TNF12.
  • 免疫原种属:
    Homo sapiens (Human)
  • 克隆类型:
    Polyclonal
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB,IHC,IF
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
  • 基因功能参考文献:
    1. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    2. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  • 亚细胞定位:
    Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
  • 蛋白家族:
    Tumor necrosis factor family
  • 组织特异性:
    Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
  • 数据库链接:

    HGNC: 11927

    OMIM: 602695

    KEGG: hsa:407977

    UniGene: Hs.54673