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TNFSF12 Antibody

  • 货号：
    CSB-PA023987ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA023987ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human epityphlon tissue using CSB-PA023987ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TNFSF12 Polyclonal antibody
  • Uniprot No.：
    O43508
  • 基因名：
    TNFSF12
  • 别名：
    APO 3 ligand antibody; APO 3L antibody; APO3 ligand antibody; APO3/DR3 ligand antibody; APO3L antibody; DR3LG antibody; MGC129581 antibody; MGC20669 antibody; secreted form antibody; TNF-related weak inducer of apoptosis antibody; TNF12_HUMAN antibody; TNFSF 12 antibody; Tnfsf12 antibody; TNFSF12 protein antibody; Tumor necrosis factor (ligand) superfamily member 12 antibody; Tumor necrosis factor ligand superfamily member 12 antibody; Tumor necrosis factor superfamily member 12 antibody; TWEAK antibody; UNQ181/PRO207 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tumor necrosis factor ligand superfamily member 12 protein (42-123AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
  • 基因功能参考文献：
    1. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    2. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    Tumor necrosis factor family
  • 组织特异性：
    Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
  • 数据库链接：

    HGNC: 11927

    OMIM: 602695

    KEGG: hsa:407977

    UniGene: Hs.54673