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PPP2R3B Antibody

  • 货号：
    CSB-PA896533ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA896533ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PPP2R3B Polyclonal antibody
  • Uniprot No.：
    Q9Y5P8
  • 基因名：
  • 别名：
    NY REN 8 antibody; NY REN 8 antigen antibody; P2R3B_HUMAN antibody; PP2A B'' subunit PR48 antibody; PP2A subunit B isoform PR48 antibody; PP2A subunit B PR48 isoform antibody; PPP2R3B antibody; PPP2R3L antibody; PPP2R3LY antibody; PR 48 antibody; PR48 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' beta antibody; Protein phosphatase 2 regulatory subunit B'' beta antibody; Protein phosphatase 2A 48 kDa regulatory subunit antibody; Serine/threonine protein phosphatase 2A 48kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B\'\' subunit beta protein (356-575AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能参考文献：
    1. PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6-chromatin licensing and CDT1 interaction PMID: 27974665
    2. Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2+ binding EF-hands Scattering data. PMID: 25007185
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 13417

    OMIM: 300339

    KEGG: hsa:28227

    STRING: 9606.ENSP00000375080

    UniGene: Hs.124942