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PPP2R3B Antibody

  • 货号:
    CSB-PA945169
  • 规格:
    ¥2024
  • 图片:
    • Western blot analysis of extracts from K562 cells, using P2R3B antibody.
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) PPP2R3B Polyclonal antibody
  • Uniprot No.:
    Q9Y5P8
  • 基因名:
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human P2R3B.
  • 免疫原种属:
    Homo sapiens (Human)
  • 克隆类型:
    Polyclonal
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能参考文献:
    1. PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6-chromatin licensing and CDT1 interaction PMID: 27974665
    2. Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2+ binding EF-hands Scattering data. PMID: 25007185
  • 亚细胞定位:
    Nucleus.
  • 数据库链接:

    HGNC: 13417

    OMIM: 300339

    KEGG: hsa:28227

    STRING: 9606.ENSP00000375080

    UniGene: Hs.124942