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HEBP2 Antibody

  • 货号：
    CSB-PA896539HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA896539HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA896539HA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HEBP2 Polyclonal antibody
  • Uniprot No.：
    Q9Y5Z4
  • 基因名：
    HEBP2
  • 别名：
    C6orf34 antibody; Chromosome 6 open reading frame 34 antibody; Hebp2 antibody; HEBP2_HUMAN antibody; Heme binding protein 2 antibody; Heme-binding protein 2 antibody; Placental protein 23 antibody; PP23 antibody; Protein SOUL antibody; SOUL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Heme-binding protein 2 protein (2-205AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HEBP2 Antibody (CSB-PA896539HA01HU)，的标记方式是Non-conjugated。对于HEBP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA896539HB01HU HEBP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA896539HC01HU HEBP2 Antibody, FITC conjugated
    Biotin CSB-PA896539HD01HU HEBP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
  • 基因功能参考文献：
    1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
    2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
    3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
    4. preliminary X ray structure PMID: 19574650
  • 亚细胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    HEBP family
  • 组织特异性：
    Detected in placenta.
  • 数据库链接：

    HGNC: 15716

    OMIM: 605825

    KEGG: hsa:23593

    STRING: 9606.ENSP00000058691

    UniGene: Hs.486589