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  4. Recombinant Human Heme-binding protein 2 (HEBP2)

Recombinant Human Heme-binding protein 2 (HEBP2)

  • 中文名称：
    人HEBP2重组蛋白
  • 货号：
    CSB-YP896539HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人HEBP2重组蛋白
  • 货号：
    CSB-EP896539HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人HEBP2重组蛋白
  • 货号：
    CSB-BP896539HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人HEBP2重组蛋白
  • 货号：
    CSB-MP896539HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HEBP2
  • Uniprot No.：
  • 别名：
    C6orf34; Chromosome 6 open reading frame 34; Hebp2; HEBP2_HUMAN; Heme binding protein 2; Heme-binding protein 2; Placental protein 23; PP23; Protein SOUL; SOUL
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-205
  • 氨基酸序列
    AEPLQPDPG AAEDAAAQAV ETPGWKAPED AGPQPGSYEI RHYGPAKWVS TSVESMDWDS AIQTGFTKLN SYIQGKNEKE MKIKMTAPVT SYVEPGSGPF SESTITISLY IPSEQQFDPP RPLESDVFIE DRAEMTVFVR SFDGFSSAQK NQEQLLTLAS ILREDGKVFD EKVYYTAGYN SPVKLLNRNN EVWLIQKNEP TKENE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
  • 基因功能参考文献：
    1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
    2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
    3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
    4. preliminary X ray structure PMID: 19574650
  • 亚细胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    HEBP family
  • 组织特异性：
    Detected in placenta.
  • 数据库链接：

    HGNC: 15716

    OMIM: 605825

    KEGG: hsa:23593

    STRING: 9606.ENSP00000058691

    UniGene: Hs.486589