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HEBP2 Antibody

  • 货号：
    CSB-PA010271GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y5Z4
  • 基因名：
    HEBP2
  • 别名：
    C6orf34 antibody; Chromosome 6 open reading frame 34 antibody; Hebp2 antibody; HEBP2_HUMAN antibody; Heme binding protein 2 antibody; Heme-binding protein 2 antibody; Placental protein 23 antibody; PP23 antibody; Protein SOUL antibody; SOUL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HEBP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
  • 基因功能参考文献：
    1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
    2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
    3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
    4. preliminary X ray structure PMID: 19574650
  • 亚细胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    HEBP family
  • 组织特异性：
    Detected in placenta.
  • 数据库链接：

    HGNC: 15716

    OMIM: 605825

    KEGG: hsa:23593

    STRING: 9606.ENSP00000058691

    UniGene: Hs.486589