E7 Antibody
产品详情
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产品名称:Rabbit anti-Human papillomavirus type 18 E7 Polyclonal antibody
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Uniprot No.:P06788
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基因名:
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别名:E7Protein E7 antibody
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宿主:Rabbit
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反应种属:Human papillomavirus type 18
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免疫原:Recombinant Human papillomavirus type 18 Protein E7 protein (1-105AA)
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免疫原种属:Human papillomavirus type 18
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标记方式:Non-conjugated
本页面中的产品,E7 Antibody (CSB-PA361948LA01HMN),的标记方式是Non-conjugated。对于E7 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
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亚细胞定位:Host cytoplasm. Host nucleus.
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蛋白家族:Papillomaviridae E7 protein family
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