Recombinant Rhesus Macaque Interleukin-4 protein (IL4)
In Stock产品详情
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纯度:>96% as determined by SDS-PAGE.
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内毒素:Less than 1.0 EU/μg as determined by LAL method.
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生物活性:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0x106 IU/mg.
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基因名:
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Uniprot No.:
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别名:IL4Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
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种属:Macaca mulatta (Rhesus macaque)
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蛋白长度:Full Length of Mature Protein
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来源:E.Coli
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分子量:14.9 kDa
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表达区域:25-153aa
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氨基酸序列HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS
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蛋白标签:Tag-Free
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产品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
缓冲液:0.2 μm filtered 2 x PBS, pH 7.4, 5 % trehalose ,lyophilized
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:5-10 business days
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Datasheet & COA:Please contact us to get it.
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靶点详情
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功能:Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
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亚细胞定位:Secreted.
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蛋白家族:IL-4/IL-13 family
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数据库链接:
STRING: 9544.ENSMMUP00000004187
UniGene: Mmu.3375
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