SELE

SELE，即E选择素，它是一种细胞表面糖蛋白，由SELE基因编码，主要表达在活化的内皮细胞上。SELE的作用机制涉及其在炎症反应中的调节作用，特别是在白细胞与内皮细胞的粘附过程中。当内皮细胞受到炎症介质如肿瘤坏死因子α（TNF-α）或IL-1等刺激时，SELE表达上调，促进滚动的白细胞粘附于内皮细胞表面，并进一步迁移至炎症部位。SELE的信号通路包括与白细胞表面的配体如sialyl-Lewis X（sLe^X）相互作用，触发细胞内信号传导，增强细胞间的粘附。在生物学意义上，SELE对调控免疫细胞的迁移、参与炎症反应和免疫监视等过程至关重要。SELE的异常表达与多种病理过程有关，包括动脉粥样硬化、炎症性肠病和自身免疫性疾病等。

热销产品

Recombinant Pig E-selectin (SELE), partial (CSB-EP020975PIe1)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SELE Antibody (CSB-PA056380)

验证数据

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA056380(SELE Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA056380(SELE Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

SELE Antibody

SELE Protein

SELE ELISA Kit

SELE Antibodies

SELE for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA020975GA01HU	SELE Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA056380	SELE Antibody	Human	ELISA,IHC
CSB-PA775739	SELE Antibody	Human	ELISA,IHC
CSB-PA715369	SELE Antibody	Human	WB,ELISA

SELE for Pig

产品货号	产品名称	种属反应性	应用类型
CSB-PA020975EA01PI	SELE Antibody	Pig	ELISA
CSB-PA020975EB01PI	SELE Antibody, HRP conjugated	Pig	ELISA
CSB-PA020975EC01PI	SELE Antibody, FITC conjugated	Pig
CSB-PA020975ED01PI	SELE Antibody, Biotin conjugated	Pig	ELISA

SELE Proteins

SELE Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP020975PI	Recombinant Pig E-selectin (SELE), partial	Yeast
CSB-EP020975PI	Recombinant Pig E-selectin (SELE), partial	E.coli
CSB-BP020975PI CSB-MP020975PI CSB-EP020975PI-B	Recombinant Pig E-selectin (SELE), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SELE Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP020975BO1 CSB-EP020975BO1 CSB-BP020975BO1 CSB-MP020975BO1 CSB-EP020975BO1-B	Recombinant Bovine E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975BO	Recombinant Bovine E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP020975HU1 CSB-EP020975HU1 CSB-BP020975HU1 CSB-MP020975HU1 CSB-EP020975HU1-B	Recombinant Human E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975HU	Recombinant Human E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Oryctolagus cuniculus (Rabbit)

产品货号	产品名称	来源
CSB-YP020975RB	Recombinant Rabbit E-selectin (SELE), partial	Yeast
CSB-EP020975RB CSB-BP020975RB CSB-MP020975RB CSB-EP020975RB-B	Recombinant Rabbit E-selectin (SELE), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SELE Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

产品货号	产品名称	来源
CSB-YP020975DO1 CSB-EP020975DO1 CSB-BP020975DO1 CSB-MP020975DO1 CSB-EP020975DO1-B	Recombinant Dog E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF020975DO	Recombinant Dog E-selectin (SELE)	in vitro E.coli expression system

SELE Proteins for Equus caballus (Horse)

产品货号	产品名称	来源
CSB-YP850178HO CSB-EP850178HO CSB-BP850178HO CSB-MP850178HO CSB-EP850178HO-B	Recombinant Horse E-selectin (SELE), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli