Il5ra
IL5RA,即白细胞介素5受体亚单位α,它是一种主要表达在单核细胞、T细胞和B细胞等免疫细胞表面的细胞因子受体。IL5RA的作用机制是与IL-5配体结合,形成α链和β链的异二聚体受体复合物,进而激活下游的信号传导途径,如JAK/STAT、MAPK、PI3K和NF-κB等,调节免疫细胞的增殖、分化和功能。IL5RA对调节免疫应答、细胞分化和炎症反应等生理过程至关重要,其异常表达或功能失调与多种疾病,包括肿瘤、炎症和自身免疫性疾病的发生发展密切相关。
热销产品
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA547751(IL5RA Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
Il5ra Antibodies
Il5ra for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA011663GA01HU | IL5RA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA005144 | IL5RA Antibody | Human | WB, ELISA |
CSB-PA009557 | IL5RA Antibody | Human,Mouse | IHC, ELISA |
CSB-PA935849 | IL5RA Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA547751 | IL5RA Antibody | Human,Mouse | ELISA,WB,IHC |
Il5ra Proteins
Il5ra Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP011663MO1 CSB-EP011663MO1 CSB-BP011663MO1 CSB-MP011663MO1 CSB-EP011663MO1-B |
Recombinant Mouse Interleukin-5 receptor subunit alpha (Il5ra), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011663MO | Recombinant Mouse Interleukin-5 receptor subunit alpha (Il5ra) | in vitro E.coli expression system |