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IL5RA

IL5RA,即白细胞介素5受体亚单位α,它是一种主要表达在单核细胞、T细胞和B细胞等免疫细胞表面的细胞因子受体。IL5RA的作用机制是与IL-5配体结合,形成α链和β链的异二聚体受体复合物,进而激活下游的信号传导途径,如JAK/STAT、MAPK、PI3K和NF-κB等,调节免疫细胞的增殖、分化和功能。IL5RA对调节免疫应答、细胞分化和炎症反应等生理过程至关重要,其异常表达或功能失调与多种疾病,包括肿瘤、炎症和自身免疫性疾病的发生发展密切相关。

热销产品

IL5RA Antibody (CSB-PA547751)

验证数据

CSB-PA547751

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA547751

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA547751

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA547751(IL5RA Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

IL5RA Antibodies

IL5RA for Homo sapiens (Human)

IL5RA Proteins

IL5RA Proteins for Mus musculus (Mouse)