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CDH17

CDH17指的是胆固醇黏附素家族成员17(Cadherin-17),也被称为肝脏细胞间粘附分子(Liver-Cell Adhesion Molecule,L-CAM)。它是一种单个跨膜的细胞粘附分子,属于钙依赖性细胞粘附分子家族中的一员。CDH17主要在肝、胆管、胰腺、消化道和泌尿道等组织中表达。 CDH17的主要功能是调节细胞黏附、迁移和生长等过程,参与了多种生理和病理过程。例如,在肝胆系统中,CDH17发挥了肝细胞和胆管上皮细胞之间的黏附作用,同时还参与了胆汁酸的转运和分泌。在胰腺癌中,CDH17的高表达与肿瘤的浸润和转移有关。 因此,CDH17已成为潜在的治疗靶点,CUSABIO有多种CDH17单克隆抗体供您选择。

更多相关阅读:肠钙粘蛋白CDH17:单抗、双抗、CAR T“多管齐下”,胃肠道癌GIC重磅靶点!

热销产品

Recombinant Human Cadherin-17(CDH17),partial (Active) CSB-MP613267HU

验证数据

High Purity Validated by SDS-PAGE
CSB-MP613267HU SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA
CSB-MP613267HU AC

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 2μg/mL can bind Anti-CDH17 recombinant antibody (CSB-RA613267MA1HU), the EC50 is 3.095 to 4.451 ng/mL.

CDH17 Recombinant Monoclonal Antibody CSB-RA613267MA1HU

验证数据

Excellent Bioactivity Validated by Functional ELISA
CSB-RA613267MA1HU ELISA

The Binding Activity of Human CDH17 with Anti-CDH17 Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 (CSB-MP613267HU) at 2 μg/mL can bind Anti-CDH17 recombinant antibody, the EC50 is 3.095-4.451 ng/mL.

FC
CSB-MP613267HU FC

Untransfected HEK293T cells (green line) and transfected Human CDH17 HEK293T stable cells (red line) were stained with anti-CDH17 antibody (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

CDH17 Antibodies

CDH17 for Homo sapiens (Human)

CDH17 Proteins

CDH17 Proteins for Rattus norvegicus (Rat)

CDH17 Proteins for Homo sapiens (Human)

CDH17 Proteins for Mus musculus (Mouse)