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DNAL4 Antibody

  • 货号：
    CSB-PA007046LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: DNAL4 antibody at 1.5µg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: HL60 whole cell lysate
      Lane 3: NIH/3T3 whole cell lysate
      Lane 4: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 13 kDa
      Observed band size: 13 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA007046LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007046LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA007046LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    CUSABIO uses the recombinant human DNAL4 protein (1-105AA) to immunize rabbits and then purify the rabbit antiserum through antigen affinity purification to obtain the anti-DNAL4 antibody. This DNAL4 antibody is a polyclonal antibody and occurs as an unconjugated IgG. It shows reactivity with human and mouse DNAL4 protein, a component of the outer dynein arms complex which acts as the molecular motor to provide the force to move cilia in an ATP-dependent manner. And this anti-DNAL4 antibody can be used in ELISA, WB, IHC, and IF for the detection of the DNAL4 protein.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DNAL4 Polyclonal antibody
  • Uniprot No.：
    O96015
  • 基因名：
    DNAL4
  • 别名：
    D15Ertd424e antibody; Dnal4 antibody; DNAL4_HUMAN antibody; Dnalc4 antibody; Dynein axonemal light chain 4 antibody; Dynein light chain 4; axonemal antibody; Dynein light chain; outer arm 4 antibody; Dynein; axonemal; light 4 antibody; Dynein; axonemal; light polypeptide 4 antibody; MGC105573 antibody; PIG27 antibody; Proliferation inducing gene 27 antibody; Proliferation inducing protein 27 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Dynein light chain 4, axonemal protein (1-105AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DNAL4 Antibody (CSB-PA007046LA01HU)，的标记方式是Non-conjugated。对于DNAL4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007046LB01HU DNAL4 Antibody, HRP conjugated ELISA
    FITC CSB-PA007046LC01HU DNAL4 Antibody, FITC conjugated
    Biotin CSB-PA007046LD01HU DNAL4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.
  • 基因功能参考文献：
    1. No mutation in DNAL4 in Congenital mirror movements. PMID: 25236653
    2. DNAL4 may play a role in the cytoplasmic dynein complex for netrin-1-directed retrograde transport, and in commissural neurons of the corpus callosum in particular. This could lead to faulty cross-brain wiring, resulting in Mirror movements (MRMV). PMID: 25098561
  • 相关疾病：
    Mirror movements 3 (MRMV3)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, cilium axoneme.
  • 蛋白家族：
    Dynein light chain family
  • 数据库链接：

    HGNC: 2955

    OMIM: 610565

    KEGG: hsa:10126

    STRING: 9606.ENSP00000216068

    UniGene: Hs.632766