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DNAL4 Antibody

  • 货号：
    CSB-PA006388
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    O96015
  • 基因名：
    DNAL4
  • 别名：
    D15Ertd424e antibody; Dnal4 antibody; DNAL4_HUMAN antibody; Dnalc4 antibody; Dynein axonemal light chain 4 antibody; Dynein light chain 4; axonemal antibody; Dynein light chain; outer arm 4 antibody; Dynein; axonemal; light 4 antibody; Dynein; axonemal; light polypeptide 4 antibody; MGC105573 antibody; PIG27 antibody; Proliferation inducing gene 27 antibody; Proliferation inducing protein 27 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Dynein LC 4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.
  • 基因功能参考文献：
    1. No mutation in DNAL4 in Congenital mirror movements. PMID: 25236653
    2. DNAL4 may play a role in the cytoplasmic dynein complex for netrin-1-directed retrograde transport, and in commissural neurons of the corpus callosum in particular. This could lead to faulty cross-brain wiring, resulting in Mirror movements (MRMV). PMID: 25098561
  • 相关疾病：
    Mirror movements 3 (MRMV3)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, cilium axoneme.
  • 蛋白家族：
    Dynein light chain family
  • 数据库链接：

    HGNC: 2955

    OMIM: 610565

    KEGG: hsa:10126

    STRING: 9606.ENSP00000216068

    UniGene: Hs.632766