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ZNF420 Antibody

  • 货号：
    CSB-PA007396
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of K562 cells using ZNF420 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8TAQ5
  • 基因名：
    ZNF420
  • 别名：
    ZNF420 antibody; Zinc finger protein 420 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ZNF420.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in transcriptional regulation.
  • 基因功能参考文献：
    1. Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK. PMID: 25961932
    2. ARF coordinates Apak to regulate ribosome biogenesis upon cellular stress. PMID: 25691462
    3. Apak is differentially regulated in the ARF and ATM-dependent manner in response to oncogenic stress and DNA damage, respectively. PMID: 20713054
    4. four of seven types of DNA damage signals examined resulted in significant Apak phosphorylation and dissociation of Apak from p53, releasing the inhibition of p53 transcriptional activity PMID: 19629643
    5. Apak (ZNF420 or FLJ32191) is a negative regulator of p53-mediated apoptosis. PMID: 19377469

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 20649

    KEGG: hsa:147923

    STRING: 9606.ENSP00000338770

    UniGene: Hs.444992