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ZNF420 Antibody

  • 货号:
    CSB-PA570335
  • 规格:
    ¥2024
  • 图片:
    • Western blot analysis of extracts from K562 cells, using ZNF420 antibody.
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) ZNF420 Polyclonal antibody
  • Uniprot No.:
    Q8TAQ5
  • 基因名:
    ZNF420
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human ZNF420.
  • 免疫原种属:
    Homo sapiens (Human)
  • 克隆类型:
    Polyclonal
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    May be involved in transcriptional regulation.
  • 基因功能参考文献:
    1. Functional importance of H3K9me3 in hypoxia, apoptosis and repression of APAK. PMID: 25961932
    2. ARF coordinates Apak to regulate ribosome biogenesis upon cellular stress. PMID: 25691462
    3. Apak is differentially regulated in the ARF and ATM-dependent manner in response to oncogenic stress and DNA damage, respectively. PMID: 20713054
    4. four of seven types of DNA damage signals examined resulted in significant Apak phosphorylation and dissociation of Apak from p53, releasing the inhibition of p53 transcriptional activity PMID: 19629643
    5. Apak (ZNF420 or FLJ32191) is a negative regulator of p53-mediated apoptosis. PMID: 19377469

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  • 亚细胞定位:
    Nucleus.
  • 数据库链接:

    HGNC: 20649

    KEGG: hsa:147923

    STRING: 9606.ENSP00000338770

    UniGene: Hs.444992