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USP46 Antibody

  • 货号：
    CSB-PA025738LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of A549 cells with CSB-PA025738LA01HU at 1:267, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) USP46 Polyclonal antibody
  • Uniprot No.：
    P62068
  • 基因名：
    USP46
  • 别名：
    Deubiquitinating enzyme 46 antibody; FLJ11850 antibody; FLJ12552 antibody; FLJ14283 antibody; FLJ39393 antibody; Ubiquitin carboxyl terminal hydrolase 46 antibody; Ubiquitin carboxyl-terminal hydrolase 46 antibody; Ubiquitin specific peptidase 46 antibody; Ubiquitin specific processing protease 46 antibody; Ubiquitin specific protease 46 antibody; Ubiquitin thioesterase 46 antibody; Ubiquitin thiolesterase 46 antibody; Ubiquitin-specific-processing protease 46 antibody; UBP46_HUMAN antibody; USP46 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 46 protein (66-166AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，USP46 Antibody (CSB-PA025738LA01HU)，的标记方式是Non-conjugated。对于USP46 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA025738LB01HU USP46 Antibody, HRP conjugated ELISA
    FITC CSB-PA025738LC01HU USP46 Antibody, FITC conjugated
    Biotin CSB-PA025738LD01HU USP46 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
  • 基因功能参考文献：
    1. Results suggest role for USP46/USP12 in Epstein-Barr virus induced growth transformation. PMID: 25855980
    2. USP46-mediated stabilization of PHLPP and the subsequent inhibition of Akt. PMID: 22391563
    3. results suggest that the USP46 gene might play a role in the pathophysiology of major depressive disorder in the Japanese population. PMID: 21663972
    4. These data argue against the presence of any strong genetic susceptibility factors for bipolar disorder or schizophrenia in the region USP46. PMID: 20111060
  • 蛋白家族：
    Peptidase C19 family, USP12/USP46 subfamily
  • 组织特异性：
    Broadly expressed.
  • 数据库链接：

    HGNC: 20075

    OMIM: 612849

    KEGG: hsa:64854

    STRING: 9606.ENSP00000407818

    UniGene: Hs.7966