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USP46 Antibody

  • 货号：
    CSB-PA025738GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P62068
  • 基因名：
    USP46
  • 别名：
    Deubiquitinating enzyme 46 antibody; FLJ11850 antibody; FLJ12552 antibody; FLJ14283 antibody; FLJ39393 antibody; Ubiquitin carboxyl terminal hydrolase 46 antibody; Ubiquitin carboxyl-terminal hydrolase 46 antibody; Ubiquitin specific peptidase 46 antibody; Ubiquitin specific processing protease 46 antibody; Ubiquitin specific protease 46 antibody; Ubiquitin thioesterase 46 antibody; Ubiquitin thiolesterase 46 antibody; Ubiquitin-specific-processing protease 46 antibody; UBP46_HUMAN antibody; USP46 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human USP46
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
  • 基因功能参考文献：
    1. Results suggest role for USP46/USP12 in Epstein-Barr virus induced growth transformation. PMID: 25855980
    2. USP46-mediated stabilization of PHLPP and the subsequent inhibition of Akt. PMID: 22391563
    3. results suggest that the USP46 gene might play a role in the pathophysiology of major depressive disorder in the Japanese population. PMID: 21663972
    4. These data argue against the presence of any strong genetic susceptibility factors for bipolar disorder or schizophrenia in the region USP46. PMID: 20111060
  • 蛋白家族：
    Peptidase C19 family, USP12/USP46 subfamily
  • 组织特异性：
    Broadly expressed.
  • 数据库链接：

    HGNC: 20075

    OMIM: 612849

    KEGG: hsa:64854

    STRING: 9606.ENSP00000407818

    UniGene: Hs.7966