UBE2G1 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) UBE2G1 Polyclonal antibody
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Uniprot No.:P62253
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基因名:
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别名:E217K antibody; UB2G1_HUMAN antibody; UBC 7 antibody; UBC7 antibody; UBC7 homolog yeast antibody; UBE 2G antibody; UBE2G antibody; Ube2g1 antibody; Ubiquitin carrier protein G1 antibody; Ubiquitin conjugating enzyme E2 G1 antibody; Ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C. elegans) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast) antibody; Ubiquitin conjugating enzyme E2G 1 antibody; Ubiquitin protein ligase G1 antibody; Ubiquitin-conjugating enzyme E2 G1 antibody; Ubiquitin-protein ligase G1 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Ubiquitin-conjugating enzyme E2 G1 protein (2-170AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,UBE2G1 Antibody (CSB-PA025453LA01HU),的标记方式是Non-conjugated。对于UBE2G1 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC, IF
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推荐稀释比:
Application Recommended Dilution IHC 1:500-1:1000 IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
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基因功能参考文献:
- ubiquitin binding by the acidic loops of Ube2g1 and Ube2r1 enzymes distinguishes their Lys-48-ubiquitylation activities PMID: 25471371
- study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively PMID: 21628527
- In endoplasmic reticulum, involved in the degradation of type 2 iodothyronine selenodeiodinase PMID: 12933904
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蛋白家族:Ubiquitin-conjugating enzyme family
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组织特异性:Widely expressed, mainly in skeletal muscle.
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数据库链接:
HGNC: 12482
OMIM: 601569
KEGG: hsa:7326
STRING: 9606.ENSP00000380178
UniGene: Hs.741319