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UBE2G1 Antibody

  • 货号：
    CSB-PA060036
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P62253
  • 基因名：
  • 别名：
    E217K antibody; UB2G1_HUMAN antibody; UBC 7 antibody; UBC7 antibody; UBC7 homolog yeast antibody; UBE 2G antibody; UBE2G antibody; Ube2g1 antibody; Ubiquitin carrier protein G1 antibody; Ubiquitin conjugating enzyme E2 G1 antibody; Ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C. elegans) antibody; Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast) antibody; Ubiquitin conjugating enzyme E2G 1 antibody; Ubiquitin protein ligase G1 antibody; Ubiquitin-conjugating enzyme E2 G1 antibody; Ubiquitin-protein ligase G1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human UBE2G1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
  • 基因功能参考文献：
    1. ubiquitin binding by the acidic loops of Ube2g1 and Ube2r1 enzymes distinguishes their Lys-48-ubiquitylation activities PMID: 25471371
    2. study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively PMID: 21628527
    3. In endoplasmic reticulum, involved in the degradation of type 2 iodothyronine selenodeiodinase PMID: 12933904
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 组织特异性：
    Widely expressed, mainly in skeletal muscle.
  • 数据库链接：

    HGNC: 12482

    OMIM: 601569

    KEGG: hsa:7326

    STRING: 9606.ENSP00000380178

    UniGene: Hs.741319