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TBR1 Antibody

  • 货号：
    CSB-PA023242GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q16650
  • 基因名：
    TBR1
  • 别名：
    T box brain 1 antibody; T box brain protein 1 antibody; T brain 1 protein antibody; T-box brain protein 1 antibody; T-brain-1 antibody; TBR 1 antibody; TBR-1 antibody; Tbr1 antibody; TBR1_HUMAN antibody; TES 56 antibody; TES-56 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TBR1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons.
  • 基因功能参考文献：
    1. TBR1 homodimerizes; it interacts with FOXP2, a transcription factor implicated in speech/language disorders, and this interaction is disrupted by pathogenic mutations affecting either protein PMID: 25232744
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Brain.
  • 数据库链接：

    HGNC: 11590

    OMIM: 604616

    KEGG: hsa:10716

    STRING: 9606.ENSP00000374205

    UniGene: Hs.210862