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SRPK3 Antibody

  • 货号：
    CSB-PA914515
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA914515(SRPK3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA914515(SRPK3 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes
  • 其他：

产品详情

  • Uniprot No.：
    Q9UPE1
  • 基因名：
    SRPK3
  • 别名：
    MSSK-1 antibody; MSSK1 antibody; Muscle specific serine kinase 1 antibody; Muscle-specific serine kinase 1 antibody; Serine/arginine rich protein specific kinase 3 antibody; Serine/arginine-rich protein-specific kinase 3 antibody; Serine/threonine protein kinase 23 antibody; Serine/threonine protein kinase SRPK3 antibody; Serine/threonine-protein kinase 23 antibody; SFRS protein kinase 3 antibody; SR-protein-specific kinase 3 antibody; Srpk3 antibody; SRPK3_HUMAN antibody; SRSF protein kinase 3 antibody; STK 23 antibody; STK23 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human SRPK3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.
  • 基因功能参考文献：
    1. SRPK3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. Alternative splicing of the alpha-exon of MEF2C regulates myogenesis. Loss of SRPK3 in rhabdomyosarcoma cells inhibits this splicing and blocks differentiation. PMID: 25404735
  • 蛋白家族：
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family
  • 组织特异性：
    Exclusively expressed in skeletal and heart muscle.
  • 数据库链接：

    HGNC: 11402

    OMIM: 301002

    KEGG: hsa:26576

    STRING: 9606.ENSP00000359119

    UniGene: Hs.104865