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SRPK3 Antibody

  • 货号：
    CSB-PA008774
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9UPE1
  • 基因名：
    SRPK3
  • 别名：
    MSSK-1 antibody; MSSK1 antibody; Muscle specific serine kinase 1 antibody; Muscle-specific serine kinase 1 antibody; Serine/arginine rich protein specific kinase 3 antibody; Serine/arginine-rich protein-specific kinase 3 antibody; Serine/threonine protein kinase 23 antibody; Serine/threonine protein kinase SRPK3 antibody; Serine/threonine-protein kinase 23 antibody; SFRS protein kinase 3 antibody; SR-protein-specific kinase 3 antibody; Srpk3 antibody; SRPK3_HUMAN antibody; SRSF protein kinase 3 antibody; STK 23 antibody; STK23 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human SRPK3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.
  • 基因功能参考文献：
    1. SRPK3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. Alternative splicing of the alpha-exon of MEF2C regulates myogenesis. Loss of SRPK3 in rhabdomyosarcoma cells inhibits this splicing and blocks differentiation. PMID: 25404735
  • 蛋白家族：
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family
  • 组织特异性：
    Exclusively expressed in skeletal and heart muscle.
  • 数据库链接：

    HGNC: 11402

    OMIM: 301002

    KEGG: hsa:26576

    STRING: 9606.ENSP00000359119

    UniGene: Hs.104865