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  4. SMOC2 Antibody

SMOC2 Antibody

  • 货号：
    CSB-PA169309
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA169309(SMOC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA169309(SMOC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: CSB-PA169309(SMOC2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

产品详情

  • Uniprot No.：
    Q9H3U7
  • 基因名：
    SMOC2
  • 别名：
    bA270C4A.1 antibody; bA37D8.1 (secreted modular calcium binding protein 2) antibody; bA37D8.1 antibody; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) antibody; dJ421D16.1 antibody; MST117 antibody; MSTP117 antibody; MSTP140 antibody; Secreted modular calcium binding protein 2 antibody; Secreted modular calcium-binding protein 2 antibody; SMAP 2 antibody; SMAP-2 antibody; SMAP2 antibody; SMOC 2 antibody; SMOC-2 antibody; SMOC2 antibody; SMOC2_HUMAN antibody; Smooth muscle associated protein 2 antibody; Smooth muscle-associated protein 2 antibody; SPARC related modular calcium binding 2 antibody; SPARC-related modular calcium-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SMOC2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.
  • 基因功能参考文献：
    1. SMOC2 was highly expressed in both peritoneal and endometrioma lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue. PMID: 28678915
    2. The expression of Smoc2 was significantly higher in hepatocellular carcinoma (HCC) tissues compared with corresponding non-tumor liver tissues. Smoc2 promotes the proliferation of HCC cells through accelerating cell cycle progression. PMID: 28018113
    3. L1-mediated CRC progression involves the acquisition of a stem cell-like phenotype, and that SMOC-2 elevation is necessary for L1-mediated induction of more aggressive/invasive CRC properties. PMID: 25915847
    4. could not detect an association between SMOC2 gene and AMD. This study tests the candidacy of SMOC2 gene to the etiology of AMD PMID: 22964816
    5. SMOC2 SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism. PMID: 23463390
    6. mutation in exon 8 of the SMOC2 gene linked to oligodontia PMID: 23317772
    7. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects PMID: 22152679
    8. The variant rs13208776 in SMOC2 gene does not play a major role in increasing the risk of vitiligo in Jordanian Arab patients. PMID: 20965805
    9. SMOC2 is a risk locus for generalized vitiligo and perhaps other autoimmune diseases PMID: 19890347
    10. identification of gene, chromosome mapping PMID: 12741954
    11. SMOC-2 is a novel angiogenic factor that potentiates angiogenic effects of growth factors PMID: 16774925
    12. We tested association between SMOC2 polymorphisms and FEV(1) and FVC. SMOC2 might play an important role in the determination of FEV(1) and FVC PMID: 17204727
    13. Although this study specifies rat, the s studied and discussed the human gene in this study as well. PMID: 12031507

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  • 相关疾病：
    Dentin dysplasia 1 (DTDP1)
  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 数据库链接：

    HGNC: 20323

    OMIM: 125400

    KEGG: hsa:64094

    STRING: 9606.ENSP00000346537

    UniGene: Hs.487200