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SH3GL3 Antibody

  • 货号：
    CSB-PA860359ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA860359ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SH3GL3 Polyclonal antibody
  • Uniprot No.：
    Q99963
  • 基因名：
  • 别名：
    CNSA3 antibody; EEN 2B L3 antibody; EEN B2 antibody; EEN-B2 antibody; EEN2BL3 antibody; EENB2 antibody; Endophilin 3 antibody; Endophilin A3 antibody; Endophilin-3 antibody; Endophilin-A3 antibody; H.sapiens mRNA for protein containing SH3 domain, SH3GL3 antibody; HsT19371 antibody; SH3 domain containing GRB2 like protein 3 antibody; SH3 domain GRB2 like 3 antibody; SH3 domain protein 2C antibody; SH3 domain-containing GRB2-like protein 3 antibody; SH3D2C antibody; SH3G3_HUMAN antibody; SH3GL3 antibody; SH3P13 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Endophilin-A3 protein (1-270AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
  • 基因功能参考文献：
    1. Our findings indicate that SH3GL3 plays an important role in myeloma cell migration/invasion, stemness and chemo-resistance. The SH3GL3-mediated myeloma cell migration/invasion is mediated by FAK/PI3K signaling pathway. PMID: 27683032
    2. Aberrant DNA methylation of SH3GL3 gene is associated with colorectal cancer. PMID: 22901147
    3. SH3GL3 as a novel glioma invasion-associated candidate gene that likely contribute to the invasive phenotype of malignant gliomas. PMID: 21722156
    4. These data implicate ataxin-2 to play a role in endocytic receptor cycling.[Endophilin A3] PMID: 18602463
    5. importance of hapln1b and sh3gl3 in embryonic vascular development PMID: 19308258

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  • 亚细胞定位：
    Cytoplasm. Early endosome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Endophilin family
  • 组织特异性：
    Brain and testis.
  • 数据库链接：

    HGNC: 10832

    OMIM: 603362

    KEGG: hsa:6457

    STRING: 9606.ENSP00000391372

    UniGene: Hs.270055