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RCAN2 Antibody

  • 货号：
    CSB-PA239101
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA239101(RCAN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q14206
  • 基因名：
    RCAN2
  • 别名：
    Calcipressin 2 antibody; Calcipressin-2 antibody; CSP2 antibody; Down syndrome candidate region 1-like 1 antibody; Down syndrome critical region gene 1 like 1 protein antibody; DSCR1L1 antibody; MCIP2 antibody; Myocyte enriched calcineurin interacting protein 2 antibody; Myocyte-enriched calcineurin-interacting protein 2 antibody; RCAN2 antibody; RCAN2_HUMAN antibody; RCN2 antibody; Regulator of calcineurin 2 antibody; Thyroid hormone responsive gene ZAKI4 antibody; Thyroid hormone responsive protein ZAKI4 antibody; thyroid hormone-responsive (skin fibroblasts) antibody; Thyroid hormone-responsive protein ZAKI-4 antibody; ZAKI4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human RCAN2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
  • 基因功能参考文献：
    1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression PMID: 19819266
    3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. PMID: 12102656
    4. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. PMID: 17610901
  • 蛋白家族：
    RCAN family
  • 组织特异性：
    Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
  • 数据库链接：

    HGNC: 3041

    OMIM: 604876

    KEGG: hsa:10231

    STRING: 9606.ENSP00000329454

    UniGene: Hs.440168