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RCAN2 Antibody

  • 货号：
    CSB-PA019501GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q14206
  • 基因名：
    RCAN2
  • 别名：
    Calcipressin 2 antibody; Calcipressin-2 antibody; CSP2 antibody; Down syndrome candidate region 1-like 1 antibody; Down syndrome critical region gene 1 like 1 protein antibody; DSCR1L1 antibody; MCIP2 antibody; Myocyte enriched calcineurin interacting protein 2 antibody; Myocyte-enriched calcineurin-interacting protein 2 antibody; RCAN2 antibody; RCAN2_HUMAN antibody; RCN2 antibody; Regulator of calcineurin 2 antibody; Thyroid hormone responsive gene ZAKI4 antibody; Thyroid hormone responsive protein ZAKI4 antibody; thyroid hormone-responsive (skin fibroblasts) antibody; Thyroid hormone-responsive protein ZAKI-4 antibody; ZAKI4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human RCAN2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
  • 基因功能参考文献：
    1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression PMID: 19819266
    3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. PMID: 12102656
    4. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. PMID: 17610901
  • 蛋白家族：
    RCAN family
  • 组织特异性：
    Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
  • 数据库链接：

    HGNC: 3041

    OMIM: 604876

    KEGG: hsa:10231

    STRING: 9606.ENSP00000329454

    UniGene: Hs.440168