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Phospholipase A2 Antibody

  • 货号：
    CSB-PA018091ZA01DNK
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: Phospholipase A2 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 20 kDa
      Observed band size: 20 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Apis mellifera (Honeybee) Phospholipase A2 Polyclonal antibody
  • Uniprot No.：
    P00630
  • 基因名：
    Phospholipase A2
  • 别名：
    Phospholipase A2 (bvPLA2) (EC 3.1.1.4) (Allergen Api m I) (Phosphatidylcholine 2-acylhydrolase) (allergen Api m 1)
  • 宿主：
    Rabbit
  • 反应种属：
    Apis mellifera
  • 免疫原：
    Recombinant Apis mellifera Phospholipase A2 protein (34-167)
  • 免疫原种属：
    Apis mellifera (Honeybee)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
  • 基因功能参考文献：
    1. PLA(2)s were located on the membrane surface rather than penetrating the membrane bilayer and that the deeply inserted mode is not a favorable condition for the hydrolysis of phospholipids in zwitterionic phospholipid membranes. PMID: 21557547
    2. contributions of the individual disulfide bonds to conformational stability PMID: 20884319
    3. successive introduction of sequence modifications outside the human and murine T cell epitope regions led to a progressive loss of specific IgE and IgG reactivity PMID: 15459335
    4. Studies with bee venom (bv) mutant PLA2 show that electrostatic interactions between lysine and arginine residues and anionic phosphatidylserine contribute minimally to overall interfacial binding energetics of bvPLA2. PMID: 15491136
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Phospholipase A2 family, Group III subfamily
  • 组织特异性：
    Expressed by the venom gland.
  • 数据库链接：

    KEGG: ame:406141

    STRING: 7460.GB13351-PA

    UniGene: Ame.2