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PLK5 Antibody

  • 货号：
    CSB-PA003821
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using PLK-5 Polyclonal Antibody
    • Western Blot analysis of Jurkat K562 NIH-3T3 cells using PLK-5 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q496M5
  • 基因名：
    PLK5
  • 别名：
    PLK5 antibody; PLK5P antibody; FG060302 antibody; Inactive serine/threonine-protein kinase PLK5 antibody; Polo-like kinase 5 antibody; PLK-5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PLK-5.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
  • 基因功能参考文献：
    1. we report a three-nucleotide deletion near the C-region of Plk5 that is specifically associated with the lymphatic metastasis in patients with clear cell renal cell carcinoma PMID: 26908440
    2. The human polo-like kinase 5 gene is significantly silenced in astrocytoma and glioblastoma multiforme by promoter hypermethylation, suggesting a tumor suppressor function for this gene. PMID: 21245385
  • 亚细胞定位：
    Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily
  • 组织特异性：
    Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in t
  • 数据库链接：

    HGNC: 27001

    KEGG: hsa:126520

    STRING: 9606.ENSP00000466248

    UniGene: Hs.195352