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PLA2G12A Antibody

  • 货号：
    CSB-PA018086GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BZM1
  • 基因名：
  • 别名：
    EC 3.1.1.4 antibody; Group XII secreted phospholipase A2 antibody; Group XIIA secreted phospholipase A2 antibody; Group XIIA secretory phospholipase A2 antibody; Group XIIA secretory phospholipase A2 precursor antibody; GXII antibody; GXII sPLA2 antibody; PG12A_HUMAN antibody; phosphatidylcholine 2 acylhydrolase 12A antibody; Phosphatidylcholine 2 acylhydrolase GXII antibody; Phosphatidylcholine 2-acylhydrolase 12A antibody; Phospholipase A2 group XIIA antibody; PLA2G12 antibody; Pla2g12a antibody; ROSSY antibody; sPLA2 XII antibody; sPLA2-XII antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PLA2G12A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
  • 基因功能参考文献：
    1. The study demonstrated that PLA2G12A SNPs or haplotypes might influence the susceptibility to schizophrenia in the Han Chinese population from Northeast China. PMID: 27434078
    2. cellular arachidonate (AA) release and prostaglandin (PG) production are regulated by novel classes of secretory phospholipase A(2)s (sPLA(2)s), groups III and XII PMID: 12522102
  • 亚细胞定位：
    Secreted. Cytoplasm.
  • 蛋白家族：
    Phospholipase A2 family
  • 组织特异性：
    Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
  • 数据库链接：

    HGNC: 18554

    OMIM: 611652

    KEGG: hsa:81579

    STRING: 9606.ENSP00000243501

    UniGene: Hs.389452