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NR2C2AP Antibody

  • 货号：
    CSB-PA016053LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NR2C2AP antibody at 4µg/ml + HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 16, 20 kDa
      Observed band size: 20 kDa
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA016053LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA016053LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NR2C2AP Polyclonal antibody
  • Uniprot No.：
    Q86WQ0
  • 基因名：
    NR2C2AP
  • 别名：
    nr2c2ap antibody; NR2CA_HUMAN antibody; Nuclear receptor 2C2 associated protein antibody; Nuclear receptor 2C2-associated protein antibody; Repressor for TR4 transactivation antibody; TR4 orphan receptor associated 16 kDa protein antibody; TR4 orphan receptor associated protein TRA16 antibody; TR4 orphan receptor-associated 16 kDa protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Nuclear receptor 2C2-associated protein (7-139AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NR2C2AP Antibody (CSB-PA016053LA01HU)，的标记方式是Non-conjugated。对于NR2C2AP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA016053LB01HU NR2C2AP Antibody, HRP conjugated ELISA
    FITC CSB-PA016053LC01HU NR2C2AP Antibody, FITC conjugated
    Biotin CSB-PA016053LD01HU NR2C2AP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
  • 基因功能参考文献：
    1. High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2 PMID: 23129017
    2. TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation PMID: 12486131
    3. Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells. PMID: 15381082
    4. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression. PMID: 17054912
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    NR2C2AP family
  • 组织特异性：
    Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas.
  • 数据库链接：

    HGNC: 30763

    OMIM: 608719

    KEGG: hsa:126382

    STRING: 9606.ENSP00000332823

    UniGene: Hs.708153