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NETO1 Antibody

  • 货号：
    CSB-PA840571LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, U87 whole cell lysate
      All lanes: NETO1 antibody at 3.2μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 61, 18 kDa
      Observed band size: 61 kDa
    • Immunofluorescence staining of HepG2 cells with CSB-PA840571LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NETO1 Polyclonal antibody
  • Uniprot No.：
    Q8TDF5
  • 基因名：
    NETO1
  • 别名：
    AI851453 antibody; BCTL1 antibody; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody; BTCL1 antibody; C130005O10Rik antibody; FLJ41325 antibody; Neto1 antibody; NETO1_HUMAN antibody; Neuropilin and tolloid like 1 antibody; Neuropilin and tolloid-like protein 1 antibody; RGD1566269 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Neuropilin and tolloid-like protein 1 protein (367-507AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，NETO1 Antibody (CSB-PA840571LA01HU)，的标记方式是Non-conjugated。对于NETO1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA840571LB01HU NETO1 Antibody, HRP conjugated ELISA
    FITC CSB-PA840571LC01HU NETO1 Antibody, FITC conjugated
    Biotin CSB-PA840571LD01HU NETO1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
  • 基因功能参考文献：
    1. Neto1 is concluded to be a component of amyloid precursor protein /NMDA receptor trafficking complexes PMID: 23621516
    2. no evidence for the association of NETO1 with schizophrenia in the Japanese population PMID: 22205981
    3. Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses. PMID: 19243221
  • 亚细胞定位：
    [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.
  • 组织特异性：
    Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.
  • 数据库链接：

    HGNC: 13823

    OMIM: 607973

    KEGG: hsa:81832

    STRING: 9606.ENSP00000313088

    UniGene: Hs.465407