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  4. Recombinant Human Neuropilin and tolloid-like protein 1 (NETO1), partial

Recombinant Human Neuropilin and tolloid-like protein 1 (NETO1), partial

  • 中文名称：
    人NETO1重组蛋白
  • 货号：
    CSB-YP840571HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NETO1重组蛋白
  • 货号：
    CSB-EP840571HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NETO1重组蛋白
  • 货号：
    CSB-EP840571HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NETO1重组蛋白
  • 货号：
    CSB-BP840571HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NETO1重组蛋白
  • 货号：
    CSB-MP840571HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NETO1
  • Uniprot No.：
  • 别名：
    AI851453; BCTL1; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 ; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1; BTCL1; C130005O10Rik; FLJ41325; Neto1; NETO1_HUMAN; Neuropilin and tolloid like 1; Neuropilin and tolloid-like protein 1; RGD1566269
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
  • 基因功能参考文献：
    1. Neto1 is concluded to be a component of amyloid precursor protein /NMDA receptor trafficking complexes PMID: 23621516
    2. no evidence for the association of NETO1 with schizophrenia in the Japanese population PMID: 22205981
    3. Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses. PMID: 19243221
  • 亚细胞定位：
    [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.
  • 组织特异性：
    Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.
  • 数据库链接：

    HGNC: 13823

    OMIM: 607973

    KEGG: hsa:81832

    STRING: 9606.ENSP00000313088

    UniGene: Hs.465407