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MTX1 Antibody

  • 货号：
    CSB-PA015211GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13505
  • 基因名：
    MTX1
  • 别名：
    MTX1; MTX; MTXN; Metaxin-1; Mitochondrial outer membrane import complex protein 1
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MTX1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
  • 基因功能参考文献：
    1. after the induction of apoptosis, Bak switches from its association with Mtx2 and VDAC2 to a closer association with Mtx1. PMID: 27845183
    2. Results describe the association between the MTX1 and beta-glucocerebrosidase genes and its possible effect on Parkinson disease. PMID: 21837367
    3. Single Nucleotide Polymorphism in metaxin 1 is associated with Gaucher disease PMID: 15024629
    4. The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved. PMID: 17510655
    5. mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
  • 蛋白家族：
    Metaxin family
  • 数据库链接：

    HGNC: 7504

    OMIM: 600605

    KEGG: hsa:4580

    STRING: 9606.ENSP00000357360

    UniGene: Hs.490874