MTX1 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) MTX1 Polyclonal antibody
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Uniprot No.:Q13505
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基因名:MTX1
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别名:MTX1; MTX; MTXN; Metaxin-1; Mitochondrial outer membrane import complex protein 1
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Metaxin-1 protein (217-466AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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产品提供形式:Liquid
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应用范围:ELISA, WB
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推荐稀释比:
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
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基因功能参考文献:
- after the induction of apoptosis, Bak switches from its association with Mtx2 and VDAC2 to a closer association with Mtx1. PMID: 27845183
- Results describe the association between the MTX1 and beta-glucocerebrosidase genes and its possible effect on Parkinson disease. PMID: 21837367
- Single Nucleotide Polymorphism in metaxin 1 is associated with Gaucher disease PMID: 15024629
- The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved. PMID: 17510655
- mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330
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亚细胞定位:Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
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蛋白家族:Metaxin family
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数据库链接:
HGNC: 7504
OMIM: 600605
KEGG: hsa:4580
STRING: 9606.ENSP00000357360
UniGene: Hs.490874