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MKX Antibody

  • 货号：
    CSB-PA818257LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate
      All lanes: MKX antibody at 6µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 40 kDa
      Observed band size: 40 kDa
    • IHC image of CSB-PA818257LA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA818257LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MKX Polyclonal antibody
  • Uniprot No.：
    Q8IYA7
  • 基因名：
    MKX
  • 别名：
    9430023B20Rik antibody; C10orf48 antibody; Homeobox protein Mohawk antibody; IFRX antibody; Iroquois family related homeodomain protein antibody; iroquois homeobox protein like 1 antibody; IRXL1 antibody; MGC39616 antibody; MKX antibody; MKX_HUMAN antibody; mohawk homeobox antibody; OTTHUMP00000019374 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Homeobox protein Mohawk protein (157-305AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MKX Antibody (CSB-PA818257LA01HU)，的标记方式是Non-conjugated。对于MKX Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA818257LB01HU MKX Antibody, HRP conjugated ELISA
    FITC CSB-PA818257LC01HU MKX Antibody, FITC conjugated
    Biotin CSB-PA818257LD01HU MKX Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a morphogenetic regulator of cell adhesion.
  • 基因功能参考文献：
    1. Data show that homeobox protein Mohawk (Mkx) is mainly expressed in the outer annulus fibrosus (OAF) of humans and mice. PMID: 27527664
    2. these data shed light on previously unrecognized roles of Mkx in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta pathway. PMID: 25332192
    3. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. PMID: 25312837
    4. Reduced expression of MKX is a feature of degenerated anterior cruciate ligament in osteoarthritis-affected joints. PMID: 23686683
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20634891
    6. In silico characterization of the C10orf48 sequence PMID: 16077953

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TALE/IRO homeobox family
  • 数据库链接：

    HGNC: 23729

    KEGG: hsa:283078

    STRING: 9606.ENSP00000364946

    UniGene: Hs.128193