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  4. Recombinant Human Homeobox protein Mohawk (MKX)

Recombinant Human Homeobox protein Mohawk (MKX)

  • 中文名称：
    人MKX重组蛋白
  • 货号：
    CSB-YP818257HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MKX重组蛋白
  • 货号：
    CSB-EP818257HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MKX重组蛋白
  • 货号：
    CSB-EP818257HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MKX重组蛋白
  • 货号：
    CSB-BP818257HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MKX重组蛋白
  • 货号：
    CSB-MP818257HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MKX
  • Uniprot No.：
  • 别名：
    9430023B20Rik; C10orf48; Homeobox protein Mohawk; IFRX; Iroquois family related homeodomain protein; iroquois homeobox protein like 1; IRXL1; MGC39616; MKX; MKX_HUMAN; mohawk homeobox; OTTHUMP00000019374
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-352
  • 氨基酸序列
    MNTIVFNKLS GAVLFEDGGA SERERGGRPY SGVLDSPHAR PEVGIPDGPP LKDNLGLRHR RTGARQNGGK VRHKRQALQD MARPLKQWLY KHRDNPYPTK TEKILLALGS QMTLVQVSNW FANARRRLKN TVRQPDLSWA LRIKLYNKYV QGNAERLSVS SDDSCSEDGE NPPRTHMNEG GYNTPVHHPV IKSENSVIKA GVRPESRASE DYVAPPKYKS SLLNRYLNDS LRHVMATNTT MMGKTRQRNH SGSFSSNEFE EELVSPSSSE TEGNFVYRTD TLENGSNKGE SAANRKGPSK DDTYWKEINA AMALTNLAQG KDKLQGTTSC IIQKSSHIAE VKTVKVPLVQ QF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as a morphogenetic regulator of cell adhesion.
  • 基因功能参考文献：
    1. Data show that homeobox protein Mohawk (Mkx) is mainly expressed in the outer annulus fibrosus (OAF) of humans and mice. PMID: 27527664
    2. these data shed light on previously unrecognized roles of Mkx in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta pathway. PMID: 25332192
    3. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. PMID: 25312837
    4. Reduced expression of MKX is a feature of degenerated anterior cruciate ligament in osteoarthritis-affected joints. PMID: 23686683
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20634891
    6. In silico characterization of the C10orf48 sequence PMID: 16077953

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TALE/IRO homeobox family
  • 数据库链接：

    HGNC: 23729

    KEGG: hsa:283078

    STRING: 9606.ENSP00000364946

    UniGene: Hs.128193