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LGALS12 Antibody

  • 货号：
    CSB-PA846606LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Rat kidney tissue
      All lanes: LGALS12 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 38, 32, 37, 30, 36 kDa
      Observed band size: 38 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA846606LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846606LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品描述：
    LGALS12 polyclonal antibody CSB-PA846606LA01HU was produced in the rabbit immunized by using the Recombinant Human Galectin-12 protein (1-336AA) as the immunogen. The target protein LGALS12, a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. It can bind lactose and May participate in the apoptosis of adipocytes. The related mouse protein is a primary regulator of the early stages of adipose tissue development.
    This Rabbit anti-Homo sapiens (Human) LGALS12 Polyclonal antibody was tested in the ELISA, WB and IHC applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the LGALS12 proteins of human or rat-origin and may be used to detect the endogenous levels of LGALS12 protein.
  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LGALS12 Polyclonal antibody
  • Uniprot No.：
    Q96DT0
  • 基因名：
    LGALS12
  • 别名：
    Gal-12 antibody; Galectin related inhibitor of proliferation antibody; Galectin-12 antibody; Galectin-related inhibitor of proliferation antibody; GRIP1 antibody; Lectin galactoside binding soluble 12 (galectin 12) antibody; LEG12_HUMAN antibody; Lgals12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Galectin-12 protein (1-336AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LGALS12 Antibody (CSB-PA846606LA01HU)，的标记方式是Non-conjugated。对于LGALS12 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846606LB01HU LGALS12 Antibody, HRP conjugated ELISA
    FITC CSB-PA846606LC01HU LGALS12 Antibody, FITC conjugated
    Biotin CSB-PA846606LD01HU LGALS12 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds lactose. May participate in the apoptosis of adipocytes.
  • 基因功能参考文献：
    1. Galectin-12 is silenced in colorectal cancer via hypermethylation of its promoter. PMID: 29098769
    2. Overexpression of galectin-12 contributes to a differentiation block in acute promyelocytic leukemia cells, and suppression of galectin-12 facilitates granulocytic differentiation. PMID: 27256573
    3. Lower LGALS12 gene expression is associated with acute myeloid leukemia. PMID: 25953264
    4. results suggest that mouse galectin-12 is a major regulator of adipose tissue development PMID: 15131127
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Not widely expressed. Predominantly expressed in adipose tissue.
  • 数据库链接：

    HGNC: 15788

    OMIM: 606096

    KEGG: hsa:85329

    STRING: 9606.ENSP00000339374

    UniGene: Hs.502774