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Recombinant Human Galectin-12 (LGALS12)

  • 中文名称：
    人LGALS12重组蛋白
  • 货号：
    CSB-YP846606HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人LGALS12重组蛋白
  • 货号：
    CSB-EP846606HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人LGALS12重组蛋白
  • 货号：
    CSB-EP846606HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人LGALS12重组蛋白
  • 货号：
    CSB-BP846606HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人LGALS12重组蛋白
  • 货号：
    CSB-MP846606HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LGALS12
  • Uniprot No.：
  • 别名：
    Gal-12; Galectin related inhibitor of proliferation; Galectin-12; Galectin-related inhibitor of proliferation; GRIP1; Lectin galactoside binding soluble 12 (galectin 12) ; LEG12_HUMAN; Lgals12
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-336
  • 氨基酸序列
    MSQPSGGRAP GTRIYSWSCP TVMSPGEKLD PIPDSFILQP PVFHPVVPYV TTIFGGLHAG KMVMLQGVVP LDAHRFQVDF QCGCSLCPRP DIAFHFNPRF HTTKPHVICN TLHGGRWQRE ARWPHLALRR GSSFLILFLF GNEEVKVSVN GQHFLHFRYR LPLSHVDTLG IFGDILVEAV GFLNINPFVE GSREYPAGHP FLLMSPRLEV PCSHALPQGL SPGQVIIVRG LVLQEPKHFT VSLRDQAAHA PVTLRASFAD RTLAWISRWG QKKLISAPFL FYPQRFFEVL LLFQEGGLKL ALNGQGLGAT SMNQQALEQL RELRISGSVQ LYCVHS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds lactose. May participate in the apoptosis of adipocytes.
  • 基因功能参考文献：
    1. Galectin-12 is silenced in colorectal cancer via hypermethylation of its promoter. PMID: 29098769
    2. Overexpression of galectin-12 contributes to a differentiation block in acute promyelocytic leukemia cells, and suppression of galectin-12 facilitates granulocytic differentiation. PMID: 27256573
    3. Lower LGALS12 gene expression is associated with acute myeloid leukemia. PMID: 25953264
    4. results suggest that mouse galectin-12 is a major regulator of adipose tissue development PMID: 15131127
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Not widely expressed. Predominantly expressed in adipose tissue.
  • 数据库链接：

    HGNC: 15788

    OMIM: 606096

    KEGG: hsa:85329

    STRING: 9606.ENSP00000339374

    UniGene: Hs.502774