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KCND1 Antibody

  • 货号：
    CSB-PA798293
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from 3T3 cells, using KCND1antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KCND1 Polyclonal antibody
  • Uniprot No.：
    Q9NSA2
  • 基因名：
    KCND1
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from C-terminal of Human KCND1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • 基因功能参考文献：
    1. S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation. PMID: 24675763
    2. reflected in the immunoblotting data KV4.1 receptors were detected at higher levels of expression in patient with cortical dysplasia with intractable epilepsy. PMID: 25003238
    3. These results demonstrated that Kv4.1 plays a role in proliferation of tumorigenic human mammary epithelial cells. PMID: 19401188
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell projection, dendrite.
  • 蛋白家族：
    Potassium channel family, D (Shal) (TC 1.A.1.2) subfamily, Kv4.1/KCND1 sub-subfamily
  • 组织特异性：
    Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain.
  • 数据库链接：

    HGNC: 6237

    OMIM: 300281

    KEGG: hsa:3750

    STRING: 9606.ENSP00000218176

    UniGene: Hs.55276