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KBTBD6 Antibody

  • 货号：
    CSB-PA774812LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: KBTBD6 antibody at 3.4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 77 kDa
      Observed band size: 77 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA774812LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA774812LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KBTBD6 Polyclonal antibody
  • Uniprot No.：
    Q86V97
  • 基因名：
    KBTBD6
  • 别名：
    KBTB6_HUMAN antibody; KBTBD6 antibody; Kelch repeat and BTB (POZ) domain containing 6 antibody; Kelch repeat and BTB domain-containing protein 6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Kelch repeat and BTB domain-containing protein 6 protein (1-139AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KBTBD6 Antibody (CSB-PA774812LA01HU)，的标记方式是Non-conjugated。对于KBTBD6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA774812LB01HU KBTBD6 Antibody, HRP conjugated ELISA
    FITC CSB-PA774812LC01HU KBTBD6 Antibody, FITC conjugated
    Biotin CSB-PA774812LD01HU KBTBD6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation. By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation. Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 数据库链接：

    HGNC: 25340

    OMIM: 617738

    KEGG: hsa:89890

    STRING: 9606.ENSP00000368799

    UniGene: Hs.534040