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JRK Antibody

  • 货号：
    CSB-PA525639NA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate, Mouse heart tissue
      All lanes: JRK antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 62, 63 kDa
      Observed band size: 62 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) JRK Polyclonal antibody
  • Uniprot No.：
    O75564
  • 基因名：
    JRK
  • 别名：
    JRK antibody; JH8 antibody; Jerky protein homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Peptide sequence from Human Jerky protein homolog protein (465-483AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，JRK Antibody (CSB-PA525639NA01HU)，的标记方式是Non-conjugated。对于JRK Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA525639NB01HU JRK Antibody, HRP conjugated ELISA
    FITC CSB-PA525639NC01HU JRK Antibody, FITC conjugated
    Biotin CSB-PA525639ND01HU JRK Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May bind DNA.
  • 基因功能参考文献：
    1. JRK expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin target genes and increased cell proliferation PMID: 26455321
    2. in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers PMID: 28708826
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Tigger transposable element derived protein family
  • 组织特异性：
    Expressed ubiquitously.
  • 数据库链接：

    HGNC: 6199

    OMIM: 603210

    KEGG: hsa:8629

    UniGene: Hs.535903