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  4. IL17D Antibody

IL17D Antibody

  • 货号：
    CSB-PA141453
  • 规格：
    ￥880
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100
    • Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100
    • Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100
  • 其他：

产品详情

  • Uniprot No.：
    Q8TAD2
  • 基因名：
  • 别名：
    IL 17D antibody; IL 22 antibody; IL 27 antibody; IL-17D antibody; IL-27 antibody; IL17D antibody; IL17D_HUMAN antibody; IL27 antibody; Interleukin 17D antibody; Interleukin 27 antibody; Interleukin-17D antibody; Interleukin-27 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide from Human protein at AA range: 141-190
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC,ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC IHC-p:1:50-300
    ELISA 1:10000-20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
  • 基因功能参考文献：
    1. Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
    2. Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
    3. Utilizing gene microarray analysis, s found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
    4. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
    5. IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
    6. IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    IL-17 family
  • 组织特异性：
    Expressed preferentially in adipose, skeletal muscle and CNS.
  • 数据库链接：

    HGNC: 5984

    OMIM: 607587

    KEGG: hsa:53342

    STRING: 9606.ENSP00000302924

    UniGene: Hs.655142